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Guidance programme

Advice programme

Showing 5611 to 5625 of 7707 results

  1. For people with active, drug susceptible TB who experience treatment interruptions because of adverse events, particularly hepatotoxicity, what approach to re-establishing treatment is mosteffective in reducing mortality and morbidity?

    Recommendation ID NG33/5 Question For people with active, drug susceptible TB who experience treatment interruptions because of adverse

    Research recommendation
    Published
    8 November 2019

  2. Treatment of convulsive status epilepticus (that is, not just refractory): What is the most effective and safest AED to treat: established (usually lasting longer than 30 minutes) convulsive status epilepticus refractory convulsive status epilepticus?

    Recommendation ID CG137/4 Question Treatment of convulsive status epilepticus (that is, not just refractory): What is the most effective

    Research recommendation
    Published
    13 August 2021

  3. Treatment of torus fractures:- What is the clinical effectiveness and cost effectiveness of no treatment for torus fractures of the distal radius in children compared with soft splints, removable splints or bandages?

    Recommendation ID NG38/5 Question Treatment of torus fractures:- What is the clinical effectiveness and cost effectiveness of no treatment

    Research recommendation
    Published
    21 March 2016

  4. What is the most effective first-line treatment option for any severity of acne vulgaris for people with polycystic ovary syndrome?

    Recommendation ID NG198/2 Question What is the most effective first-line treatment option for any severity of acne vulgaris for people

    Research recommendation
    Published
    3 May 2024

  5. In people with suspected TB, what is the relative clinical and cost effectiveness of universal andrisk-based use of rapid nucleic acid amplification tests?

    Recommendation ID NG33/1 Question In people with suspected TB, what is the relative clinical and cost effectiveness of universal andrisk-based

    Research recommendation
    Published
    8 November 2019

  6. Trials that evaluate utility values (using generic preference-based measures) in children and young people with severe psoriasis are needed to better inform future cost–utility analyses.

    Recommendation ID TA455/1 Question Trials that evaluate utility values (using generic preference-based measures) in children and young

    Research recommendation
    Published
    15 October 2018

  7. How effective and cost effective are universal, education-based alcohol interventions for children and young people aged 11 to 25 with SEND?

    Recommendation ID NG135/3 Question How effective and cost effective are universal, education-based alcohol interventions for children and

    Research recommendation
    Published
    25 October 2019

  8. Truncal treatment with or without concurrent tributary treatment:- What is the clinical and cost effectiveness of concurrent phlebectomies or foam sclerotherapy for varicose tributaries during truncal endothermal ablation for varicose veins compared with: - truncal endothermal ablation without concurrent phlebectomies or foam sclerotherapy? - truncal endothermal ablation with phlebectomies or foam sclerotherapy, if needed, 6–12 weeks later?

    Recommendation ID CG168/4 Question Truncal treatment with or without concurrent tributary treatment:- What is the clinical and cost effectiveness

    Research recommendation
    Published
    9 June 2015

  9. Unknown primary of presumed upper aerodigestive tract origin:- In people with CUADT of unknown primary, can radiotherapy target volumes be selected based on clinical and pathological factors?

    Recommendation ID NG36/3 Question Unknown primary of presumed upper aerodigestive tract origin:- In people with CUADT of unknown primary

    Research recommendation
    Published
    6 April 2016

  10. Few women use contraception perfectly (that is, exactly in accordance with the product instructions) and consistently. Pregnancy rates during typical use reflect effectiveness of a method among women who use the method incorrectly or inconsistently. Few data are available on typical use of any contraceptive method among women in the UK. Much of the data on contraceptive effectiveness used in the guideline come from clinical trials or surveys undertaken in other countries such as the USA. Large prospective cohort studies are needed to compare the contraceptive effectiveness of LARC methods with non‑LARC methods during typical use in the UK.

    Recommendation ID CG30/1 Question Few women use contraception perfectly (that is, exactly in accordance with the product instructions)

    Research recommendation
    Published
    25 October 2019

  11. Diagnosis: The GDG recommends that a UK study of the performance characteristics and cost-effectiveness of procalcitonin versus C-reactive protein in identifying serious bacterial infection in children with fever without apparent source be carried out.

    Recommendation ID NG143/03 Question Diagnosis: The GDG recommends that a UK study of the performance characteristics and cost-effectiveness

    Research recommendation
    Published
    17 December 2021

  12. Management according to risk of serious illness: The GDG recommends that research is carried out on referral patterns between primary and secondary care for children with fever, so the health economic impact of this and future guidelines can be estimated.

    Recommendation ID NG143/07 Question Management according to risk of serious illness: The GDG recommends that research is carried out on

    Research recommendation
    Published
    17 December 2021

  13. The evidence on transvaginal laser therapy for stress urinary incontinence does not show any short-term safety concerns. Evidence on long-term safety andefficacy is inadequate in quality and quantity. Therefore, this procedure should only be used in the context of research. Find out what only in research means onthe NICE interventional procedures guidance page.

    Recommendation ID IPG696/1 Question The evidence on transvaginal laser therapy for stress urinary incontinence does not show any short-term

    Research recommendation
    Published
    10 August 2021

  14. The evidence on transvaginal laser therapy for urogenital atrophy does not show any short-term safety concerns. Evidence on long-term safety and efficacy is inadequate in quality and quantity. Therefore, this procedure should only be used in the context of research. Find out what only in research means on the NICE interventional procedures guidance page.

    Recommendation ID IPG697/1 Question The evidence on transvaginal laser therapy for urogenital atrophy does not show any short-term safety

    Research recommendation
    Published
    10 August 2021

  15. Antipyretics: The GDG recommends that studies are conducted in primary care and secondary care to determine whether examination or re-examination after a dose of antipyretic medication is of benefit in differentiating children with serious illness from those with other conditions.

    Recommendation ID NG143/04 Question Antipyretics: The GDG recommends that studies are conducted in primary care and secondary care to determine

    Research recommendation
    Published
    17 December 2021