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Area of interest

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Last updated

Guidance programme

Advice programme

Showing 4741 to 4755 of 7685 results

  1. Research is needed to establish the efficacy and tolerability of bile acid sequestrants among people with irritable bowel syndrome (IBS-D) or Crohn's disease without ileal resection.

    Recommendation ID DG7/3 Question Research is needed to establish the efficacy and tolerability of bile acid sequestrants among people with

    Research recommendation
    Published
    9 June 2015

  2. Research is recommended on HumiGard compared with standard insufflation gases in patients having laparoscopic or open surgery alongside general measures to reduce the risk of perioperative hypothermia (described in section 2.5). Research should report on the comparative rate of surgical site infections and other complications associated with hypothermia and normothermia, as well as related resource use.

    Recommendation ID MTG31/1 Question Research is recommended on HumiGard compared with standard insufflation gases in patients having laparoscopic

    Research recommendation
    Published
    26 April 2017

  3. Research is needed to establish the nature of bile acid malabsorption and whether bile acid malabsorption is a primary or secondary condition in people diagnosed with irritable bowel syndrome (IBS-D) or Crohn's disease without ileal resection.

    Recommendation ID DG7/2 Question Research is needed to establish the nature of bile acid malabsorption and whether bile acid malabsorption

    Research recommendation
    Published
    9 June 2015

  4. Research is recommended on patient preferences, and their impact on quality of life, for contrast-enhanced ultrasound and other imaging modalities. Ideally such research should compare all appropriate imaging modalities in the same patient group.

    Recommendation ID DG5/2 Question Research is recommended on patient preferences, and their impact on quality of life, for contrast-enhanced

    Research recommendation
    Published
    9 June 2015

  5. Research is needed to establish the validity and accuracy of the SeHCAT (tauroselcholic [75selenium] acid) test and of any potential alternative technologies for measuring bile acid malabsorption in people with chronic diarrhoea diagnosed with irritable bowel syndrome (IBS-D) or Crohn's disease without ileal resection.

    Recommendation ID DG7/1 Question Research is needed to establish the validity and accuracy of the SeHCAT (tauroselcholic [75selenium] acid)

    Research recommendation
    Published
    9 June 2015

  6. Research is recommended on the percentage of unenhanced ultrasound scans that are inconclusive, particularly in people with cirrhosis. Such studies should explicitly define and describe why scans are 'inconclusive'.

    Recommendation ID DG5/1 Question Research is recommended on the percentage of unenhanced ultrasound scans that are inconclusive, particularly

    Research recommendation
    Published
    9 June 2015

  7. Research is recommended to address uncertainties about the claimed benefits of using Mepilex Border Heel and Sacrum dressings. This research should also explore issues such as:- the incidence of heel and sacrum pressure ulcers in NHS acute care settings- criteria for patient selection to reduce pressure ulcer incidence with Mepilex Border Heel and Sacrum dressings in addition to standard care.NICE will consider reviewing this guidance when substantive new evidence becomes available.

    Recommendation ID MTG40/1 Question Research is recommended to address uncertainties about the claimed benefits of using Mepilex Border

    Research recommendation
    Published
    7 March 2019

  8. Research is needed to generate robust and relevant data on the effects of treating people with Alzheimer's disease on both short-term and long-term outcomes, disease progression through relevant health states, and quality of life.

    Recommendation ID TA217/1 Question Research is needed to generate robust and relevant data on the effects of treating people with Alzheimer's

    Research recommendation
    Published
    9 June 2015

  9. Research is needed to quantify the health outcome benefits associated with imaging improvements with the EOS system. Examples of such benefits might include reduced back pain or reduced postural difficulties in people with scoliosis, or longer lasting and less painful joint replacements. Although research into the use of the EOS system is appropriate for all the indications included in the scope, the research most likely to be useful is for planning hip and knee replacement, including patient selection, device selection, and surgical approach. Joint replacement operations are more common than the other indications and the EOS system is thought to be most likely to provide benefit to these patients.

    Recommendation ID DG1/1 Question Research is needed to quantify the health outcome benefits associated with imaging improvements with the

    Research recommendation
    Published
    9 June 2015

  10. Research is recommended to address uncertainties about the claimed patient and system benefits of the ReCell Spray-On Skin system. Clinical outcomes should include time to 95% healing, length of hospital stay, cosmetic appearance of the scar and function of the burned area, compared with standard care.

    Recommendation ID MTG21/1 Question Research is recommended to address uncertainties about the claimed patient and system benefits of the

    Research recommendation
    Published
    9 June 2015

  11. Research is recommended in the UK clinical setting to compare the BRAHMS copeptin assay in combination with cardiac troponin testing against sequential cardiac troponin testing for ruling out myocardial infarction.

    Recommendation ID MTG4/1 Question Research is recommended in the UK clinical setting to compare the BRAHMS copeptin assay in combination

    Research recommendation
    Published
    9 June 2015

  12. Research is recommended to address uncertainties about the claimed patient and system benefits of using Parafricta Bootees and Undergarments.

    Recommendation ID MTG20/1 Question Research is recommended to address uncertainties about the claimed patient and system benefits of using

    Research recommendation
    Published
    10 August 2021

  13. Research is recommended to address uncertainties in the potential benefits to patients and the NHS of using VibraTip. Research is needed into the diagnostic accuracy of VibraTip compared with the 10 g monofilament and calibrated tuning fork in the diagnosis of peripheral neuropathy in people with diabetes. This research should also address the assessment of vibration perception compared with touch sensation in this clinical context.

    Recommendation ID MTG22/1 Question Research is recommended to address uncertainties in the potential benefits to patients and the NHS of

    Research recommendation
    Published
    9 June 2015

  14. Research on second-line treatments for transitional cell carcinoma of the urothelial tract is needed. It noted that the vinflunine studies were the only studies in patients with transitional cell carcinoma of the urothelial tract whose disease had progressed after platinum-based chemotherapy. It was noted that there is a lack of evidence for the relative effectiveness of treatment options at this stage in the pathway of care. It is recommended that studies be undertaken to investigate the relative safety and efficacy of second-line treatments for transitional cell carcinoma of the urothelial tract, particularly randomised controlled trials.

    Recommendation ID TA272/1 Question Research on second-line treatments for transitional cell carcinoma of the urothelial tract is needed

    Research recommendation
    Published
    9 June 2015

  15. Research on the safety and efficacy of superior capsular augmentation for massive rotator cuff tears should address patient selection, type of graft and technique used,long-term outcomes including shoulder function, and patient-reported outcome measures.

    Recommendation ID IPG619/1 Question Research on the safety and efficacy of superior capsular augmentation for massive rotator cuff tears

    Research recommendation
    Published
    19 December 2018