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Guidance programme

Advice programme

Showing 5446 to 5460 of 7681 results

  1. NICE recommended the collection of data on prosthesis failure or on the prevalence of people living with a failed hip but for whom revision surgery is not suitable or who choose not to have revision surgery. NICE further recommended that nomenclature for hip replacement failure needs to be established to allow demarcation of prosthesis-dependent and prosthesisindependent hip replacement failure. Furthermore, patient reported outcome measures collected as part of the National Joint Registry should allow for reporting of hip replacement failure in people who cannot or choose not to have revision surgery.

    Recommendation ID TA304/2 Question NICE recommended the collection of data on prosthesis failure or on the prevalence of people living

    Research recommendation
    Published
    9 June 2015

  2. NICE recommends further research comparing the clinical effectiveness of all 3 viscoelastometric devices (ROTEM, TEG and Sonoclot systems) in cardiac surgery and in the emergency control of bleeding after trauma and during postpartum haemorrhage. In particular, NICE recommends research to determine which of the parameters included in the viscoelastometric testing systems are the most significant in changing clinical decision-making and improving clinical outcomes. The degree of change needed in these parameters to affect clinical decision-making and clinical outcomes should also be considered.

    Recommendation ID DG13/3 Question NICE recommends further research comparing the clinical effectiveness of all 3 viscoelastometric devices

    Research recommendation
    Published
    9 June 2015

  3. NICE recommends further research in using viscoelastometric testing in the emergency control of bleeding after trauma and during postpartum haemorrhage to assess its effectiveness compared with standard laboratory testing. NICE recommends that outcomes should include, but may not be limited to, bleeding outcomes, mortality, duration of hospital or intensive care unit stay, transfusion rates and volumes transfused.

    Recommendation ID DG13/2 Question NICE recommends further research in using viscoelastometric testing in the emergency control of bleeding

    Research recommendation
    Published
    9 June 2015

  4. NICE recommends further research to better inform future cost-effectiveness models of relapsing-remitting multiple sclerosis. In particular, this research should include a more comprehensive synthesis of available evidence on the underlying disease progression of multiple sclerosis in the UK context, the impact of disability and relapses on preference-based measures of quality of life, and associated resource use and costs.

    Recommendation ID TA320/1 Question NICE recommends further research to better inform future cost-effectiveness models of relapsing-remitting

    Research recommendation
    Published
    9 June 2015

  5. NICE recommends further research to demonstrate the utility of the Sonoclot system in detecting, managing and monitoring haemostasis in cardiac surgery.

    Recommendation ID DG13/1 Question NICE recommends further research to demonstrate the utility of the Sonoclot system in detecting, managing

    Research recommendation
    Published
    9 June 2015

  6. NICE recommends further research to establish optimal target dose ranges for 5-FU plasma levels in people with head and neck cancer, stomach cancer and pancreatic cancer.

    Recommendation ID DG16/3 Question NICE recommends further research to establish optimal target dose ranges for 5-FU plasma levels in people

    Research recommendation
    Published
    9 June 2015

  7. NICE recommends further research to investigate the clinical effectiveness of the integrated sensor-augmented insulin pump therapy systems in younger children and pregnant women. No data are currently available for these subgroups and their inclusion in future studies is encouraged.

    Recommendation ID DG21/2 Question NICE recommends further research to investigate the clinical effectiveness of the integrated sensor-augmented

    Research recommendation
    Published
    11 April 2016

  8. NICE recommends further research to quantify the impact of hypoglycaemia on quality of life for people with type 1 diabetes and their carers.Future research should include adults and children and should capture the impact of persistent anxiety associated with the fear of catastrophic events related to severe hypoglycaemic events.

    Recommendation ID DG21/1 Question NICE recommends further research to quantify the impact of hypoglycaemia on quality of life for people

    Research recommendation
    Published
    11 April 2016

  9. NICE recommends further research to understand the characteristics of patients at high risk of haemostatic instability in whom viscoelastometric testing may be most cost effective.

    Recommendation ID DG13/5 Question NICE recommends further research to understand the characteristics of patients at high risk of haemostatic

    Research recommendation
    Published
    9 June 2015

  10. NICE recommends further research to validate the accuracy and precision of the My5-FU assay for the quantitative determination of 5-fluorouracil (5-FU) at the lower end of its measuring range with analytical reference standard methods, including high-performance liquid chromatography and liquid chromatography-mass spectrometry.

    Recommendation ID DG16/1 Question NICE recommends further research to validate the accuracy and precision of the My5-FU assay for the quantitative

    Research recommendation
    Published
    9 June 2015

  11. NICE recommends research generating and analysing observational data including, but not limited to, the existing UK ITP Registry, which collects data on the long-term outcomes of patients treated with eltrombopag and romiplostim.

    Recommendation ID TA293/2 Question NICE recommends research generating and analysing observational data including, but not limited to,

    Research recommendation
    Published
    9 June 2015

  12. [NICE] recommends research into the long-term effects of bisphosphonates on bone quality, given the inhibitory effects on bone resorption of these drugs.

    Recommendation ID TA161/2 Question [NICE] recommends research into the long-term effects of bisphosphonates on bone quality, given the

    Research recommendation
    Published
    9 June 2015

  13. NICE recommends that a national registry is developed to collect data on the use of the RD-100i OSNA system in detecting sentinel lymph node metastases during breast cancer surgery. It also recommends that data on all patients having whole lymph node analysis by the RD-100i OSNA system should be submitted to this registry. These data should be integrated with data from other registries for breast cancer where appropriate.

    Recommendation ID DG8/1 Question NICE recommends that a national registry is developed to collect data on the use of the RD-100i OSNA system

    Research recommendation
    Published
    9 June 2015

  14. NICE recommends that a new model for multiple sclerosis is developed, ideally based on UK patient cohorts, which uses the best available evidence (including experience to date from the risk-sharing scheme) and includes all currently available treatments.

    Recommendation ID TA254/2 Question NICE recommends that a new model for multiple sclerosis is developed, ideally based on UK patient cohorts

    Research recommendation
    Published
    9 June 2015

  15. NICE recommends that studies directly comparing different epidermal growth factor receptor tyrosine kinase (EGFR-TK) mutation test methods are performed. These studies should include the re-testing of stored non-small-cell lung cancer (NSCLC) tumour samples using different EGFR-TK mutation test methods and should link to patient outcomes.

    Recommendation ID DG9/1 Question NICE recommends that studies directly comparing different epidermal growth factor receptor tyrosine kinase

    Research recommendation
    Published
    9 June 2015