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Guidance programme

Advice programme

Showing 5656 to 5670 of 7679 results

  1. Treating small oesophageal varices:- Do non-selective beta-blockers improve survival and prevent first variceal bleeds in people with cirrhosis that is associated with small oesophageal varices?

    Recommendation ID NG50/2 Question Treating small oesophageal varices:- Do non-selective beta-blockers improve survival and prevent first

    Research recommendation
    Published
    25 August 2016

  2. What is the cost effectiveness and safety of non-surgical ablation and stereotactic body radiotherapy compared to resection for people with metastatic colorectal cancer in the lung amenable to local treatment?

    Recommendation ID NG151/1 Question What is the cost effectiveness and safety of non-surgical ablation and stereotactic body radiotherapy

    Research recommendation
    Published
    10 February 2020

  3. Treatment for people with an IOP of 22 or 23 mmHg:- What is the clinical and cost effectiveness of treating an intraocular pressure (IOP) of 22 or 23 mmHg in people with normal optic discs and visual fields?

    Recommendation ID NG81/6 Question Treatment for people with an IOP of 22 or 23 mmHg:- What is the clinical and cost effectiveness of treating

    Research recommendation
    Published
    1 February 2022

  4. For people with active, drug susceptible TB who experience treatment interruptions because of adverse events, particularly hepatotoxicity, what approach to re-establishing treatment is mosteffective in reducing mortality and morbidity?

    Recommendation ID NG33/5 Question For people with active, drug susceptible TB who experience treatment interruptions because of adverse

    Research recommendation
    Published
    8 November 2019

  5. Treatment of convulsive status epilepticus (that is, not just refractory): What is the most effective and safest AED to treat: established (usually lasting longer than 30 minutes) convulsive status epilepticus refractory convulsive status epilepticus?

    Recommendation ID CG137/4 Question Treatment of convulsive status epilepticus (that is, not just refractory): What is the most effective

    Research recommendation
    Published
    13 August 2021

  6. Treatment of torus fractures:- What is the clinical effectiveness and cost effectiveness of no treatment for torus fractures of the distal radius in children compared with soft splints, removable splints or bandages?

    Recommendation ID NG38/5 Question Treatment of torus fractures:- What is the clinical effectiveness and cost effectiveness of no treatment

    Research recommendation
    Published
    21 March 2016

  7. What is the most effective first-line treatment option for any severity of acne vulgaris for people with polycystic ovary syndrome?

    Recommendation ID NG198/2 Question What is the most effective first-line treatment option for any severity of acne vulgaris for people

    Research recommendation
    Published
    3 May 2024

  8. In people with suspected TB, what is the relative clinical and cost effectiveness of universal andrisk-based use of rapid nucleic acid amplification tests?

    Recommendation ID NG33/1 Question In people with suspected TB, what is the relative clinical and cost effectiveness of universal andrisk-based

    Research recommendation
    Published
    8 November 2019

  9. Trials that evaluate utility values (using generic preference-based measures) in children and young people with severe psoriasis are needed to better inform future cost–utility analyses.

    Recommendation ID TA455/1 Question Trials that evaluate utility values (using generic preference-based measures) in children and young

    Research recommendation
    Published
    15 October 2018

  10. How effective and cost effective are universal, education-based alcohol interventions for children and young people aged 11 to 25 with SEND?

    Recommendation ID NG135/3 Question How effective and cost effective are universal, education-based alcohol interventions for children and

    Research recommendation
    Published
    25 October 2019

  11. Truncal treatment with or without concurrent tributary treatment:- What is the clinical and cost effectiveness of concurrent phlebectomies or foam sclerotherapy for varicose tributaries during truncal endothermal ablation for varicose veins compared with: - truncal endothermal ablation without concurrent phlebectomies or foam sclerotherapy? - truncal endothermal ablation with phlebectomies or foam sclerotherapy, if needed, 6–12 weeks later?

    Recommendation ID CG168/4 Question Truncal treatment with or without concurrent tributary treatment:- What is the clinical and cost effectiveness

    Research recommendation
    Published
    9 June 2015

  12. Unknown primary of presumed upper aerodigestive tract origin:- In people with CUADT of unknown primary, can radiotherapy target volumes be selected based on clinical and pathological factors?

    Recommendation ID NG36/3 Question Unknown primary of presumed upper aerodigestive tract origin:- In people with CUADT of unknown primary

    Research recommendation
    Published
    6 April 2016

  13. Few women use contraception perfectly (that is, exactly in accordance with the product instructions) and consistently. Pregnancy rates during typical use reflect effectiveness of a method among women who use the method incorrectly or inconsistently. Few data are available on typical use of any contraceptive method among women in the UK. Much of the data on contraceptive effectiveness used in the guideline come from clinical trials or surveys undertaken in other countries such as the USA. Large prospective cohort studies are needed to compare the contraceptive effectiveness of LARC methods with non‑LARC methods during typical use in the UK.

    Recommendation ID CG30/1 Question Few women use contraception perfectly (that is, exactly in accordance with the product instructions)

    Research recommendation
    Published
    25 October 2019

  14. In addition to individual circumstances and needs, a woman's choice and acceptance of LARC may be influenced by potential health disbenefits (side effects and risks) as well as non‑contraceptive benefits of LARC (such as alleviation of menorrhagia). Large population studies of appropriate design are needed to determine the effect of these factors on the uptake of LARC methods and the implications for NHS resources.

    Recommendation ID CG30/3 Question In addition to individual circumstances and needs, a woman's choice and acceptance of LARC may be influenced

    Research recommendation
    Published
    25 October 2019

  15. Current evidence on the safety of ultrasound-guided high‑intensity transcutaneous focused ultrasound for symptomatic uterine fibroids shows there are well-recognised complications including skin burns. The evidence on efficacy is limited in quality. Therefore, this procedure should only be used with  special arrangements   for clinical governance, consent, and audit or research.

    Recommendation ID IPG657/1 Question Current evidence on the safety of ultrasound-guided high‑intensity transcutaneous focused ultrasound

    Research recommendation
    Published
    15 November 2019