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Showing 5026 to 5040 of 7688 results

  1. MRI-guided laser interstitial thermal therapy for drug-resistant epilepsy Interventional procedures guidance

    Recommendation ID IPG671/1 Question MRI-guided laser interstitial thermal therapy for drug-resistant epilepsy Interventional procedures

    Research recommendation
    Published
    17 March 2020

  2. Monitoring pulmonary disease:- Is lung clearance index a useful and cost-effective tool for the routine assessment and monitoring of changes in pulmonary status in people with cystic fibrosis?

    Recommendation ID NG78/3 Question Monitoring pulmonary disease:- Is lung clearance index a useful and cost-effective tool for the routine

    Research recommendation
    Published
    6 November 2018

  3. Mucoactive agents:- What is the most clinically and cost-effective dose of rhDNase (dornase alfa; recombinant human deoxyribonuclease) for people with cystic fibrosis?

    Recommendation ID NG78/6 Question Mucoactive agents:- What is the most clinically and cost-effective dose of rhDNase (dornase alfa; recombinant

    Research recommendation
    Published
    18 October 2018

  4. What is the clinical effectiveness, cost effectiveness and tolerability of pharmacological monotherapy compared with combination therapy for treating neuropathic pain?

    Recommendation ID CG173/1 Question What is the clinical effectiveness, cost effectiveness and tolerability of pharmacological monotherapy

    Research recommendation
    Published
    26 October 2020

  5. Multidimensional assessment of outcomes- How can the individual factors associated with COPD prognosis (collected from a range of sources including primary care, imaging and pulmonary rehabilitation results) be combined into a multidimensional analysis that provides accurate and useful information on prognosis?

    Recommendation ID NG115/2 Question Multidimensional assessment of outcomes- How can the individual factors associated with COPD prognosis

    Research recommendation
    Published
    6 February 2019

  6. Monotherapy versus combination therapy for treating neuropathic pain:- What is the clinical effectiveness, cost effectiveness and tolerability of pharmacological monotherapy compared with combination therapy for treating neuropathic pain?

    Recommendation ID CG173/1 Question Monotherapy versus combination therapy for treating neuropathic pain:- What is the clinical effectiveness

    Research recommendation
    Published
    9 June 2015

  7. Is the use of chlorhexidine body wash associated with increased antimicrobial resistance?

    Recommendation ID NG125/2 Question Is the use of chlorhexidine body wash associated with increased antimicrobial resistance? Any

    Research recommendation
    Published
    16 August 2019

  8. Epidemiological study on presentation and management of sepsis in England:- What is the incidence, presentation and management of sepsis in the United Kingdom?

    Recommendation ID NG51/1 Question Epidemiological study on presentation and management of sepsis in England:- What is the incidence, presentation

    Research recommendation
    Published
    25 August 2016

  9. Epidurals:- What is the clinical and cost effectiveness of image-guided compared with non-image-guided epidural injections for people with acute sciatica?

    Recommendation ID NG59/4 Question Epidurals:- What is the clinical and cost effectiveness of image-guided compared with non-image-guided

    Research recommendation
    Published
    13 February 2017

  10. Epilepsy syndromes: What are the initial and add-on AEDs of choice in the treatment of the epilepsy syndromes with onset in childhood, for example, myoclonic-astatic epilepsy and Dravet syndrome?

    Recommendation ID CG137/2 Question Epilepsy syndromes: What are the initial and add-on AEDs of choice in the treatment of the epilepsy

    Research recommendation
    Published
    13 August 2021

  11. Epiretinal brachytherapy for wet age-related macular degeneration (AMD) should only be used in the context of research. Research studies should address whether epiretinal brachytherapy reduces the progression of wet AMD and whether it can reduce the number of injections of antivascular endothelial growth factor agents (anti-VEGF) required. Long-term outcomes should be reported.

    Recommendation ID IPG415/1 Question Epiretinal brachytherapy for wet age-related macular degeneration (AMD) should only be used in the

    Research recommendation
    Published
    9 June 2015

  12. Episcissors-60 show promise for mediolateral episiotomy. But there is currently not enough evidence to support the case for routine adoption in the NHS. Research is recommended to address uncertainties about the efficacy and safety of using Episcissors-60. This research should: - determine if using Episcissors-60 in addition to other care bundle measures is more effective in achieving an optimal episiotomy angle and in preventing episiotomy-related obstetric anal sphincter injuries (OASI) than standard episiotomy scissors - include patient-reported outcome measures - address potential equality considerations by ensuring patients at greatest risk of OASI are recruited - determine the relative cost of using Episcissors-60 compared with standard episiotomy scissors.

    Recommendation ID MTG47/1 Question Episcissors-60 show promise for mediolateral episiotomy. But there is currently not enough evidence

    Research recommendation
    Published
    17 March 2020

  13. Evaluation frameworks and logic models:- Which evaluation frameworks and logic models can be used to evaluate the impact of community engagement on health and wellbeing?

    Recommendation ID NG44/2 Question Evaluation frameworks and logic models:- Which evaluation frameworks and logic models can be used to

    Research recommendation
    Published
    6 April 2016

  14. Evaluation of extensively used interventions:- Evaluate currently unevaluated but extensively used interventions for attachment difficulties.

    Recommendation ID NG26/3 Question Evaluation of extensively used interventions:- Evaluate currently unevaluated but extensively used interventions

    Research recommendation
    Published
    11 December 2015

  15. Evidence is adequate on the short-term safety and efficacy of personalised external aortic root support (PEARS) using mesh to prevent aortic root expansion and aortic dissection in people with Marfan syndrome. Evidence on long-term outcomes is limited in quantity and quality. Therefore, this procedure should only be used with special arrangements for clinical governance, consent and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page. Further research should report details of patient selection, including aortic diameter, and long-term outcomes, including evidence of disease progression, such as dilation and dissection of the aortic root.

    Recommendation ID IPG724/01 Question Evidence is adequate on the short-term safety and efficacy of personalised external aortic root support

    Research recommendation
    Published
    31 May 2022