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Showing 5431 to 5445 of 7683 results

  1. NICE encourages further research on transcutaneous stimulation of the cervical branch of the vagus nerve for cluster headache and migraine. Studies should describe whether the procedure is used for treatment or prevention, and whether it is used for cluster headache or migraine. Clinicians should clearly document details of patient selection and the treatment regimen. Outcome measures should include changes in the number and severity of cluster headache or migraine episodes, medication use, quality of life in the short and long term, side effects, acceptability, and device  durability. NICE may update this guidance on publication of further evidence.

    Recommendation ID IPG552/1 Question NICE encourages further research on transcutaneous stimulation of the cervical branch of the vagus

    Research recommendation
    Published
    6 April 2016

  2. NICE encourages further research, preferably randomised controlled trials, into percutaneous endovascular forearm arteriovenous fistula creation for haemodialysis access. This should report details of patient selection, particularly about vascular anatomy, technique used, need for training, patency of the fistula and its subsequent ease of use, and quality of life.

    Recommendation ID IPG710/01 Question NICE encourages further research, preferably randomised controlled trials, into percutaneous endovascular

    Research recommendation
    Published
    5 November 2021

  3. NICE encourages research into endovascular stentgrafting of popliteal aneurysms and may review this procedure on publication of further evidence.

    Recommendation ID IPG390/1 Question NICE encourages research into endovascular stentgrafting of popliteal aneurysms and may review this

    Research recommendation
    Published
    9 June 2015

  4. NICE encourages the company, NHS England and treatment centres to collect more evidence, particularly on the longer-term benefits and costs of eliglustat and enzyme replacement therapy for treating type 1 Gaucher disease.

    Recommendation ID HST5/1 Question NICE encourages the company, NHS England and treatment centres to collect more evidence, particularly

    Research recommendation
    Published
    12 October 2018

  5. NICE encourages the peer-reviewed publication of all further research for percutaneous balloon valvuloplasty for fetal critical aortic stenosis. Further research could be in the form of controlled trials, analysis of registry data or other observational studies. It should address patient selection, timing of the intervention and the natural history of the disease.

    Recommendation ID IPG613/1 Question NICE encourages the peer-reviewed publication of all further research for percutaneous balloon valvuloplasty

    Research recommendation
    Published
    10 December 2018

  6. NICE highlighted the importance of collecting further data within registries of patients receiving biological treatments for psoriatic arthritis to obtain information on long-term outcomes, including adverse events.

    Recommendation ID TA220/1 Question NICE highlighted the importance of collecting further data within registries of patients receiving biological

    Research recommendation
    Published
    9 June 2015

  7. NICE noted that the cost effectiveness of lenalidomide compared with standard care for people with low- or intermediate-1-risk MDS associated with an isolated deletion 5q cytogenetic abnormality when other therapeutic options are insufficient or inadequate, was sensitive to whether the patient access scheme would be realised in clinical practice. The Committee agreed that it would be critical to generate evidence to support the following: - The proportion of people who become eligible for the patient access scheme, that is, that they remain on treatment beyond 26 cycles. - The benefit of lenalidomide after 26 cycles, that is the associated overall survival and health related quality of life for those who remain on treatment beyond 26 cycles.

    Recommendation ID TA322/1 Question NICE noted that the cost effectiveness of lenalidomide compared with standard care for people with low-

    Research recommendation
    Published
    9 June 2015

  8. NICE proposes that a clinical trial is needed to establish the relative effectiveness of mannitol compared with hypertonic saline.

    Recommendation ID TA266/1 Question NICE proposes that a clinical trial is needed to establish the relative effectiveness of mannitol compared

    Research recommendation
    Published
    9 June 2015

  9. NICE recognised the importance of further clinical trials comparing the effectiveness of the tyrosine kinase inhibitors (afatinib, erlotinib and gefitinib) in EGFR mutation-positive locally advanced or metastatic NSCLC.

    Recommendation ID TA310/1 Question NICE recognised the importance of further clinical trials comparing the effectiveness of the tyrosine

    Research recommendation
    Published
    9 June 2015

  10. NICE recommended further research into the clinical effectiveness of BCM – Body Composition Monitor-guided fluid management in people with chronic kidney disease having dialysis. It noted that the ongoing BISTRO study will assess the effect of the device in people aged 18 years or over having haemodialysis. Further research should collect clinical-outcome data in the following populations:- adults (aged 18 years and over) having peritoneal dialysis- babies, children and young people (aged under 18 years) having haemodialysis- babies, children and young people (aged under 18 years) having peritoneal dialysis.

    Recommendation ID DG29/1 Question NICE recommended further research into the clinical effectiveness of BCM – Body Composition Monitor-guided

    Research recommendation
    Published
    12 October 2018

  11. NICE recommended further research to explore the impact of having experiences of patients having continuous infusion 5-FU and take into account the impact on quality of life. The potential consequences of introducing pharmacokinetic dose adjustment should also be explored.

    Recommendation ID DG16/4 Question NICE recommended further research to explore the impact of having experiences of patients having continuous

    Research recommendation
    Published
    9 June 2015

  12. NICE noted advice from clinical experts that there is variability between the faecal immunochemical tests. This may affect the number of positive and negative results reported by the tests when a single threshold is used. It recommended further research to investigate the variability between technologies and encouraged the companies to make sure that results can be standardised for use in a symptomatic population.

    Recommendation ID DG30/2 Question NICE noted advice from clinical experts that there is variability between the faecal immunochemical tests

    Research recommendation
    Published
    15 October 2018

  13. NICE recommended that clinical data, including genotype and sustained virological response at 12 weeks, are collected for all people having treatment with simeprevir in the NHS.

    Recommendation ID TA333/1 Question NICE recommended that clinical data, including genotype and sustained virological response at 12 weeks

    Research recommendation
    Published
    9 June 2015

  14. NICE recommended that clinical data, including genotype and sustained virological response at 12 weeks, is collected for all people treated with sofosbuvir in the NHS.

    Recommendation ID TA330/1 Question NICE recommended that clinical data, including genotype and sustained virological response at 12 weeks

    Research recommendation
    Published
    9 June 2015

  15. NICE recommended that data on the effect of BCM – Body Composition Monitor-guided monitoring on health-related quality of life is collected and published. Prospective within-patient studies, which record quality of life and symptoms before and after having BCM – Body Composition Monitor-guided fluid management should be considered.

    Recommendation ID DG29/2 Question NICE recommended that data on the effect of BCM – Body Composition Monitor-guided monitoring on health-related

    Research recommendation
    Published
    12 October 2018