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Showing 5161 to 5175 of 7687 results

  1. The health-related quality-of-life evidence of patients with perianal fistulas is also lacking, therefore further research is recommended. Any research should measure the effect of treatment using preference-based measures (such as use of the EQ-5D questionnaire).

    Recommendation ID TA556/2 Question The health-related quality-of-life evidence of patients with perianal fistulas is also lacking, therefore

    Research recommendation
    Published
    19 March 2019

  2. The physical health benefits of discontinuing antipsychotic medication:- What are the short- and long-term benefits to physical health of guided medication discontinuation and/or reduction in first episode psychosis and can this be achieved without major risks?

    Recommendation ID CG178/3 Question The physical health benefits of discontinuing antipsychotic medication:- What are the short- and long-term

    Research recommendation
    Published
    9 June 2015

  3. There have been no head-to-head trials of rivaroxaban compared with a low molecular weight heparin for people who have cancer and experience an acute pulmonary embolism or deep vein thrombosis. As in NICE technology appraisal guidance 261 it is recommended that further research should be carried out.

    Recommendation ID TA287/1 Question There have been no head-to-head trials of rivaroxaban compared with a low molecular weight heparin for

    Research recommendation
    Published
    9 June 2015

  4. There is a need for additional research on the management of bleeds that occur while people are receiving apixaban, rivaroxaban or dabigatran etexilate, as there are no antidotes or established treatments to stop active bleeding for these agents.

    Recommendation ID TA275/1 Question There is a need for additional research on the management of bleeds that occur while people are receiving

    Research recommendation
    Published
    9 June 2015

  5. There is a need for further evidence on the long-term outcomes of treatment with eculizumab, and on the effect of treatment in children, adolescents and during pregnancy. The Committee supports enrolment of patients into the aHUS registry and the collection of high-quality information from these registries periodically to inform treatment decisions.

    Recommendation ID HST1/2 Question There is a need for further evidence on the long-term outcomes of treatment with eculizumab, and on the

    Research recommendation
    Published
    9 June 2015

  6. What is the clinical and cost effectiveness of prednisolone, budesonide, and beclometasone in addition to aminosalicylates compared with each other and with aminosalicylate monotherapy for the induction of remission for people with mild-to-moderate ulcerative colitis?

    Recommendation ID NG130/3 Question What is the clinical and cost effectiveness of prednisolone, budesonide, and beclometasone in addition

    Research recommendation
    Published
    25 October 2019

  7. The role of families in supporting young adults discharged from children's services:- What is the most effective way of helping families to support young people who have been discharged from children's services (whether or not they meet criteria for adult services)?

    Recommendation ID NG43/2 Question The role of families in supporting young adults discharged from children's services:- What is the most

    Research recommendation
    Published
    21 March 2016

  8. The role of parents in the treatment of children and young people with social anxiety disorder:- What is the best way of involving parents in the treatment of children and young people (at different stages of development) with social anxiety disorder?

    Recommendation ID CG159/3 Question The role of parents in the treatment of children and young people with social anxiety disorder:- What

    Research recommendation
    Published
    9 June 2015

  9. The role of primary care in supporting young people discharged from children's services:- What are the most effective ways for primary care services to be involved in planning and implementing transition, and following-up young people after transfer (whether or not they meet criteria for adult services)?

    Recommendation ID NG43/3 Question The role of primary care in supporting young people discharged from children's services:- What are the

    Research recommendation
    Published
    21 March 2016

  10. The value of primary surgery for women with advanced ovarian cancer:- Research should be undertaken to determine the effectiveness of primary surgery for women with advanced ovarian cancer whose tumour cannot be fully excised.

    Recommendation ID CG122/5 Question The value of primary surgery for women with advanced ovarian cancer:- Research should be undertaken

    Research recommendation
    Published
    9 June 2015

  11. Thoracic and lumbosacral assessment tool:- After injury, what is the best method of clinical assessment to determine who needs imaging of the thoracic and lumbar spine to exclude injury to the spinal column or cord, and who is safe to discharge without risk of missing significant injury?

    Recommendation ID NG41/3 Question Thoracic and lumbosacral assessment tool:- After injury, what is the best method of clinical assessment

    Research recommendation
    Published
    4 April 2016

  12. Paediatric early warning score (PEWS) as predictors of deterioration In children with bronchiolitis can paediatric early warning score (PEWS) predict deterioration?

    Recommendation ID NG9/2 Question Paediatric early warning score (PEWS) as predictors of deterioration In children with bronchiolitis can

    Research recommendation
    Published
    6 October 2015

  13. What is the effectiveness of pain management for women who present with chronic pain 3 months after mesh surgery for stress urinary incontinence or pelvic organ prolapse?

    Recommendation ID NG123/8 Question What is the effectiveness of pain management for women who present with chronic pain 3 months after

    Research recommendation
    Published
    21 June 2019

  14. Pain management:- A randomised trial should be undertaken comparing early endoscopic ultrasound-guided neurolytic coeliac plexus (EUS-guided NCP) interventions with on-demand EUS-guided NCP interventions in people with unresectable pancreatic cancer.

    Recommendation ID NG85/4 Question Pain management:- A randomised trial should be undertaken comparing early endoscopic ultrasound-guided

    Research recommendation
    Published
    13 November 2018

  15. Pain management for patients with an acute painful sickle cell episode:- For patients with an acute painful sickle cell episode, what are the effects of different opioid formulations, adjunct pain therapies and routes of administration on pain relief and acute sickle cell complications?

    Recommendation ID CG143/1 Question Pain management for patients with an acute painful sickle cell episode:- For patients with an acute

    Research recommendation
    Published
    9 June 2015