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Showing 5611 to 5625 of 7682 results

  1. The committee noted that there was no clinical evidence showing that having sodium zirconium cyclosilicate improved length or quality of life or allowed patients to stay on optimal doses of renin-angiotensin-aldosterone system (RAAS) inhibitors. It therefore considered that it would be valuable to have studies comparing sodium zirconium cyclosilicate plus standard care with standard care alone in people with confirmed hyperkalaemia of 6.0 mmol/litre and above, and that these should investigate: mortality disease progression patterns of RAAS inhibitor use healthcare utilisation, and health-related quality of life.

    Recommendation ID TA599/1 Question The committee noted that there was no clinical evidence showing that having sodium zirconium cyclosilicate

    Research recommendation
    Published
    8 November 2019

  2. What is the clinical and cost effectiveness of cannabis-based medicinal products other than THC: CBD spray for children, young people and adults with spasticity? In particular, what is the impact of spasticity on improvements in quality of life?

    Recommendation ID NG144/5 Question What is the clinical and cost effectiveness of cannabis-based medicinal products other than THC: CBD

    Research recommendation
    Published
    10 February 2020

  3. Specialist dementia support:- What is the most effective and cost effective way to support people with dementia living at home?

    Recommendation ID NG21/4 Question Specialist dementia support:- What is the most effective and cost effective way to support people with

    Research recommendation
    Published
    13 October 2015

  4. Specialist investigation:- What specialist investigations should be conducted to exclude a diagnosis of functional dyspepsia in people with uninvestigated dyspepsia that does not respond to PPIs or H2 receptor antagonists (H2RAs) despite optimum primary care?

    Recommendation ID CG184/5 Question Specialist investigation:- What specialist investigations should be conducted to exclude a diagnosis

    Research recommendation
    Published
    9 June 2015

  5. Standard principles of infection prevention and control:- What are the barriers to compliance with the standard principles of infection prevention and control that patients and carers experience in their own homes?

    Recommendation ID CG139/1 Question Standard principles of infection prevention and control:- What are the barriers to compliance with the

    Research recommendation
    Published
    9 June 2015

  6. Which patients, other than those known to have a high risk of complications or mortality, would benefit from postoperative care in a specialist recovery area (a high-dependency unit, a post-anaesthesia care unit or an intensive care unit)?

    Recommendation ID NG180/5 Question Which patients, other than those known to have a high risk of complications or mortality, would benefit

    Research recommendation
    Published
    26 October 2020

  7. What is the most accurate prenatal screening marker for TAPS, including middle cerebral artery peak systolic velocity (MCA‑PSV)?

    Recommendation ID NG137/1 Question What is the most accurate prenatal screening marker for TAPS, including middle cerebral artery peak

    Research recommendation
    Published
    8 November 2019

  8. Self-management support for people with mental health difficulties:- Which interventions are effective in supporting self-management for people with mental health difficulties who also have a physical condition and are moving into and out of general inpatient hospital settings?

    Recommendation ID NG27/2 Question Self-management support for people with mental health difficulties:- Which interventions are effective

    Research recommendation
    Published
    29 January 2016

  9. secondary research is recommended to understand the clinical validity of enzyme-linked immunosorbent assay (ELISA) tests, that is the correlation between ELISA test results and health outcomes or states, such as remission, response, low or high disease activity or flares in rheumatoid arthritis

    Recommendation ID DG36/2 Question secondary research is recommended to understand the clinical validity of enzyme-linked immunosorbent

    Research recommendation
    Published
    25 October 2019

  10. Self-management:- What is the impact of different early intervention-focused approaches to self-management on outcomes for older people with social care needs and multiple long-term conditions?

    Recommendation ID NG22/5 Question Self-management:- What is the impact of different early intervention-focused approaches to self-management

    Research recommendation
    Published
    11 December 2015

  11. Secondary research is recommended to understand the comparative performance of different ELISA tests for therapeutic monitoring of tumour necrosis factor (TNF)‑alpha inhibitors in rheumatoid arthritis

    Recommendation ID DG36/3 Question Secondary research is recommended to understand the comparative performance of different ELISA tests

    Research recommendation
    Published
    25 October 2019

  12. Self-monitoring strategies:- Does earlier detection of the incidence of late AMD (wet active) by self-monitoring in people diagnosed with early AMD, indeterminate AMD or late AMD (dry) lead to earlier treatment and better long-term outcomes?

    Recommendation ID NG82/5 Question Self-monitoring strategies:- Does earlier detection of the incidence of late AMD (wet active) by self-monitoring

    Research recommendation
    Published
    13 November 2018

  13. Second-line maintenance therapy in children and young people (under 16):- Is maintenance therapy more effective with a paediatric low dose of ICS plus a leukotriene receptor antagonist (LTRA) or with a paediatric low dose of ICS plus a long-acting beta2 agonist (LABA) in the treatment of asthma in children and young people (under 16) who have uncontrolled asthma on a paediatric low dose of ICS alone?

    Recommendation ID NG80/7 Question Second-line maintenance therapy in children and young people (under 16):- Is maintenance therapy more

    Research recommendation
    Published
    18 October 2018

  14. SEM Scanner 200, with visual skin assessment, shows promise for preventing pressure ulcers. However, there is not enough good-quality evidence to support the case for routine adoption in the NHS. A randomised controlled trial is recommended to address uncertainties about the clinical benefits of using the scanner compared with standard risk assessment. This should assess: using the scanner plus visual skin assessment compared with visual skin assessment alone for identifying pressure ulcer risk whether changes in clinical decision making from using the scanner reduce pressure ulcer incidence the clinical benefits and resource impact of using the scanner in different care settings the clinical benefits for different skin tones how well the scanner works across populations with a range of comorbidities patient-related outcome measures.

    Recommendation ID MTG51/1 Question SEM Scanner 200, with visual skin assessment, shows promise for preventing pressure ulcers. However

    Research recommendation
    Published
    26 October 2020

  15. Serological testing in people who have IgA deficiency:- What is the sensitivity and specificity of IgG tissue transglutaminase (tTG), IgG endomysial antibodies (EMA) and IgG deamidated gliadin peptide (DGP) tests in detecting coeliac disease in people with IgA deficiency?

    Recommendation ID NG20/1 Question Serological testing in people who have IgA deficiency:- What is the sensitivity and specificity of IgG

    Research recommendation
    Published
    13 October 2015