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Area of interest

Area of interest

Type

Type

Status

Status

Last updated

Last updated

Guidance programme

Advice programme

Showing 6046 to 6060 of 7682 results

  1. NICE recommends that robust evidence be generated to show the clinical effectiveness of pharmacokinetic dose adjustment of continuous infusion 5-FU in people with colorectal cancer.

    Recommendation ID DG16/2 Question NICE recommends that robust evidence be generated to show the clinical effectiveness of pharmacokinetic

    Research recommendation
    Published
    9 June 2015

  2. Non-invasive tests for diagnosing NAFLD and advanced liver fibrosis in children and young people:- Which non-invasive tests most accurately diagnose NAFLD and advanced liver fibrosis in children and young people?

    Recommendation ID NG49/3 Question Non-invasive tests for diagnosing NAFLD and advanced liver fibrosis in children and young people:- Which

    Research recommendation
    Published
    24 August 2016

  3. Non-invasive tests for diagnosing NAFLD in adults:- Which non-invasive tests are most accurate and cost-effective in identifying non-alcoholic fatty liver disease (NAFLD) in adults with risk factors, type 2 diabetes and metabolic syndrome?

    Recommendation ID NG49/1 Question Non-invasive tests for diagnosing NAFLD in adults:- Which non-invasive tests are most accurate and cost-effective

    Research recommendation
    Published
    24 August 2016

  4. Non-invasive tests for diagnosing NASH:- Which non-invasive tests most accurately identify non-alcoholic steatohepatitis (NASH) in people with non-alcoholic fatty liver disease (NAFLD)?

    Recommendation ID NG49/2 Question Non-invasive tests for diagnosing NASH:- Which non-invasive tests most accurately identify non-alcoholic

    Research recommendation
    Published
    24 August 2016

  5. Research is needed to establish the nature of bile acid malabsorption and whether bile acid malabsorption is a primary or secondary condition in people diagnosed with irritable bowel syndrome (IBS-D) or Crohn's disease without ileal resection.

    Recommendation ID DG7/2 Question Research is needed to establish the nature of bile acid malabsorption and whether bile acid malabsorption

    Research recommendation
    Published
    9 June 2015

  6. Research is recommended on patient preferences, and their impact on quality of life, for contrast-enhanced ultrasound and other imaging modalities. Ideally such research should compare all appropriate imaging modalities in the same patient group.

    Recommendation ID DG5/2 Question Research is recommended on patient preferences, and their impact on quality of life, for contrast-enhanced

    Research recommendation
    Published
    9 June 2015

  7. Research is needed to establish the validity and accuracy of the SeHCAT (tauroselcholic [75selenium] acid) test and of any potential alternative technologies for measuring bile acid malabsorption in people with chronic diarrhoea diagnosed with irritable bowel syndrome (IBS-D) or Crohn's disease without ileal resection.

    Recommendation ID DG7/1 Question Research is needed to establish the validity and accuracy of the SeHCAT (tauroselcholic [75selenium] acid)

    Research recommendation
    Published
    9 June 2015

  8. Research is recommended on the percentage of unenhanced ultrasound scans that are inconclusive, particularly in people with cirrhosis. Such studies should explicitly define and describe why scans are 'inconclusive'.

    Recommendation ID DG5/1 Question Research is recommended on the percentage of unenhanced ultrasound scans that are inconclusive, particularly

    Research recommendation
    Published
    9 June 2015

  9. Research is recommended to address uncertainties about the claimed benefits of using Mepilex Border Heel and Sacrum dressings. This research should also explore issues such as:- the incidence of heel and sacrum pressure ulcers in NHS acute care settings- criteria for patient selection to reduce pressure ulcer incidence with Mepilex Border Heel and Sacrum dressings in addition to standard care.NICE will consider reviewing this guidance when substantive new evidence becomes available.

    Recommendation ID MTG40/1 Question Research is recommended to address uncertainties about the claimed benefits of using Mepilex Border

    Research recommendation
    Published
    7 March 2019

  10. Research is needed to generate robust and relevant data on the effects of treating people with Alzheimer's disease on both short-term and long-term outcomes, disease progression through relevant health states, and quality of life.

    Recommendation ID TA217/1 Question Research is needed to generate robust and relevant data on the effects of treating people with Alzheimer's

    Research recommendation
    Published
    9 June 2015

  11. Research is needed to quantify the health outcome benefits associated with imaging improvements with the EOS system. Examples of such benefits might include reduced back pain or reduced postural difficulties in people with scoliosis, or longer lasting and less painful joint replacements. Although research into the use of the EOS system is appropriate for all the indications included in the scope, the research most likely to be useful is for planning hip and knee replacement, including patient selection, device selection, and surgical approach. Joint replacement operations are more common than the other indications and the EOS system is thought to be most likely to provide benefit to these patients.

    Recommendation ID DG1/1 Question Research is needed to quantify the health outcome benefits associated with imaging improvements with the

    Research recommendation
    Published
    9 June 2015

  12. Research is recommended to address uncertainties about the claimed patient and system benefits of the ReCell Spray-On Skin system. Clinical outcomes should include time to 95% healing, length of hospital stay, cosmetic appearance of the scar and function of the burned area, compared with standard care.

    Recommendation ID MTG21/1 Question Research is recommended to address uncertainties about the claimed patient and system benefits of the

    Research recommendation
    Published
    9 June 2015

  13. Research is recommended in the UK clinical setting to compare the BRAHMS copeptin assay in combination with cardiac troponin testing against sequential cardiac troponin testing for ruling out myocardial infarction.

    Recommendation ID MTG4/1 Question Research is recommended in the UK clinical setting to compare the BRAHMS copeptin assay in combination

    Research recommendation
    Published
    9 June 2015

  14. Research is recommended to address uncertainties about the claimed patient and system benefits of using Parafricta Bootees and Undergarments.

    Recommendation ID MTG20/1 Question Research is recommended to address uncertainties about the claimed patient and system benefits of using

    Research recommendation
    Published
    10 August 2021

  15. Research is recommended to address uncertainties in the potential benefits to patients and the NHS of using VibraTip. Research is needed into the diagnostic accuracy of VibraTip compared with the 10 g monofilament and calibrated tuning fork in the diagnosis of peripheral neuropathy in people with diabetes. This research should also address the assessment of vibration perception compared with touch sensation in this clinical context.

    Recommendation ID MTG22/1 Question Research is recommended to address uncertainties in the potential benefits to patients and the NHS of

    Research recommendation
    Published
    9 June 2015