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Area of interest

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Last updated

Guidance programme

Advice programme

Showing 4981 to 4995 of 7688 results

  1. NICE considered that further research is needed to determine whether faecal haemoglobin levels are influenced by age, sex and medicines that increase the risk of gastrointestinal bleeding. It noted that these data could be used to further develop risk scores that include variables such as age, sex and symptoms to help determine pre-test probability. The data could also be combined with faecal haemoglobin concentration to refine management after the use of faecal immunochemical tests in primary care.

    Recommendation ID DG30/1 Question NICE considered that further research is needed to determine whether faecal haemoglobin levels are influenced

    Research recommendation
    Published
    15 October 2018

  2. More research is needed on the following key outcomes:

    Recommendation ID HTE12/1 Question More research is needed on the following key outcomes: Any explanatory notes(if applicable)

    Research recommendation
    Published
    11 January 2024

  3. NICE considered that further research on the geko device in clinical settings could focus on reducing the current uncertainties about the reduction in relative risk in the defined patient population, and allow investigation into its use in broader patient populations.

    Recommendation ID MTG19/1 Question NICE considered that further research on the geko device in clinical settings could focus on reducing

    Research recommendation
    Published
    9 June 2015

  4. Nasal suction:- What is the clinical and cost effectiveness of suction to remove secretions from the upper respiratory tract compared with minimal handling?

    Recommendation ID NG9/5 Question Nasal suction:- What is the clinical and cost effectiveness of suction to remove secretions from the upper

    Research recommendation
    Published
    6 October 2015

  5. More research is needed on using the following digital weight-management technologies:

    Recommendation ID HTE14 Question More research is needed on using the following digital weight-management technologies: Any explanatory

    Research recommendation
    Published
    11 January 2024

  6. National pre-hospital triage tool:- A national pre-hospital triage tool for major trauma should be developed and validated.

    Recommendation ID NG40/4 Question National pre-hospital triage tool:- A national pre-hospital triage tool for major trauma should be developed

    Research recommendation
    Published
    4 April 2016

  7. NICE agreed that further research was needed because there is currently no clinical- or cost-effectiveness evidence evaluating the use of Holoclar in both eyes in bilateral patients. The committee was aware of the ongoing HOLOCORE trial which is recruiting both unilateral and bilateral patients, but only evaluates the success of a second transplant in 1 eye rather than transplant success in both eyes.

    Recommendation ID TA467/1 Question NICE agreed that further research was needed because there is currently no clinical- or cost-effectiveness

    Research recommendation
    Published
    15 October 2018

  8. NICE agreed that further research would be of value to investigate factors which can predict the likelihood of rapid progression of disease and response to treatment with biological DMARDs. Factors to investigate include:- persistent elevation of inflammatory markers (such as C-reactive protein [CRP]) and- presence of erosions on X-ray and- positive for anti-citrullinated protein antibodies (ACPA).

    Recommendation ID TA375/1 Question NICE agreed that further research would be of value to investigate factors which can predict the likelihood

    Research recommendation
    Published
    15 March 2016

  9. NICE encourages further research into efficacy of extracorporeal membrane oxygenation (ECMO) for acute heart failure. This should include clear documentation of patient selection and indications for the use of ECMO. Outcome measures should include survival, quality of life and neurological status.

    Recommendation ID IPG482/1 Question NICE encourages further research into efficacy of extracorporeal membrane oxygenation (ECMO) for acute

    Research recommendation
    Published
    9 June 2015

  10. NICE encourages further research into radiofrequency ablation of the soft palate for snoring. This could take the form of data collection, with the specific aim of documenting long-term outcomes and the need for further treatment.

    Recommendation ID IPG476/1 Question NICE encourages further research into radiofrequency ablation of the soft palate for snoring. This

    Research recommendation
    Published
    9 June 2015

  11. NICE encourages further research on corticosteroid-eluting bioabsorbable stent or spacer insertion during endoscopic sinus surgery and, specifically, controlled studies designed for between-patient (rather than within-patient) comparisons. Outcomes should include symptom scores, quality of life and the need for retreatment in the long term. All complications should be reported. NICE may update this guidance on publication of further evidence.

    Recommendation ID IPG551/1 Question NICE encourages further research on corticosteroid-eluting bioabsorbable stent or spacer insertion

    Research recommendation
    Published
    6 April 2016

  12. NICE encourages further research into endoscopic radiofrequency ablation for Barrett's oesophagus with no dysplasia. Studies should define clearly the policies used for histological diagnosis. Outcomes should include complete resolution of Barrett's oesophagus, change and progression to low-grade dysplasia, high-grade dysplasia or cancer. All complications should be reported, particularly development of strictures. Comparative studies against surveillance would be useful.

    Recommendation ID IPG496/1 Question NICE encourages further research into endoscopic radiofrequency ablation for Barrett's oesophagus with

    Research recommendation
    Published
    9 June 2015

  13. NICE also considered the role of FeNO in guiding inhaled corticosteroid dosing through stepping-up and stepping-down protocols. It accepted there is a need for more evidence on which protocols offer the safest and most optimal asthma management when used in UK clinical practice. Therefore, further studies are recommended, with consideration for the different protocols and cut-off points that may be necessary in different populations.

    Recommendation ID DG12/3 Question NICE also considered the role of FeNO in guiding inhaled corticosteroid dosing through stepping-up and

    Research recommendation
    Published
    9 June 2015

  14. NICE encourages further research into radiofrequency treatment for haemorrhoids, preferably randomised controlled trials. It may update the guidance on publication of further evidence. Outcomes should include pain, secondary haemorrhage, recurrence rate, the need for repeat procedures and quality-of-life measures. Details of patient selection should also be reported.

    Recommendation ID IPG589/1 Question NICE encourages further research into radiofrequency treatment for haemorrhoids, preferably randomised

    Research recommendation
    Published
    15 October 2018

  15. NICE encourages further research into endoscopic radiofrequency ablation for squamous dysplasia of the oesophagus, including observational data collection. Studies should clearly define patient selection. Outcomes should include completeness of ablation, resolution of squamous dysplasia, progression to cancer and quality of life. All complications should be reported, particularly development of oesophageal strictures.

    Recommendation ID IPG497/1 Question NICE encourages further research into endoscopic radiofrequency ablation for squamous dysplasia of

    Research recommendation
    Published
    9 June 2015