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Showing 4291 to 4305 of 7679 results

  1. The Committee considered that rigorous data collection is needed on the life-extending benefits of lenalidomide when used in people with multiple myeloma who have received two or more prior therapies.

    Recommendation ID TA171/1 Question The Committee considered that rigorous data collection is needed on the life-extending benefits of lenalidomide

    Research recommendation
    Published
    25 October 2019

  2. In adults having elective shoulder joint replacement, what is the relative clinical and cost effectiveness of general anaesthesia, regional anaesthesia, and general combined with regional anaesthesia?

    Recommendation ID NG157/9 Question In adults having elective shoulder joint replacement, what is the relative clinical and cost effectiveness

    Research recommendation
    Published
    10 August 2020

  3. Length of observation period following emergency treatment for anaphylaxis:- For how long should a person who has received emergency treatment for anaphylaxis be observed?

    Recommendation ID CG134/3 Question Length of observation period following emergency treatment for anaphylaxis:- For how long should a person

    Research recommendation
    Published
    9 June 2015

  4. In adults having elective shoulder joint replacement with general anaesthesia, what is the clinical and cost effectiveness of supplementary local infiltration analgesia, a nerve block or regional anaesthesia?

    Recommendation ID NG157/8 Question In adults having elective shoulder joint replacement with general anaesthesia, what is the clinical

    Research recommendation
    Published
    10 August 2020

  5. What is the clinical and cost effectiveness of levothyroxine for people under 65 with symptomatic subclinical hypothyroidism?

    Recommendation ID NG145/7 Question What is the clinical and cost effectiveness of levothyroxine for people under 65 with symptomatic subclinical

    Research recommendation
    Published
    10 February 2020

  6. Lactate level for monitoring severity of shock:- Is lactate monitoring in patients with major trauma clinically and cost effective?

    Recommendation ID NG39/2 Question Lactate level for monitoring severity of shock:- Is lactate monitoring in patients with major trauma

    Research recommendation
    Published
    21 March 2016

  7. What is the clinical and cost effectiveness of levothyroxine (T4) and liothyronine (T3) combination therapy compared with T4 alone for people with hypothyroidism whose symptoms have not responded sufficiently to T4 alone? Does DiO2 polymorphism affect the response to combination therapy with T4 and T3?

    Recommendation ID NG145/1 Question What is the clinical and cost effectiveness of levothyroxine (T4) and liothyronine (T3) combination

    Research recommendation
    Published
    10 February 2020

  8. What is the effectiveness of laparoscopic fundoplication compared with medical management in people with GORD that does not respond to optimal proton pump inhibitor (PPI) treatment?

    Recommendation ID CG184/2 Question What is the effectiveness of laparoscopic fundoplication compared with medical management in people

    Research recommendation
    Published
    15 November 2019

  9. Lifestyle interventions (diet and exercise):- Are specialist lifestyle interventions (diet and exercise) effective, compared with no specialist lifestyle interventions, for women with endometriosis?

    Recommendation ID NG73/3 Question Lifestyle interventions (diet and exercise):- Are specialist lifestyle interventions (diet and exercise)

    Research recommendation
    Published
    15 October 2018

  10. Laparoscopic fundoplication compared with medical management:- What is the effectiveness of laparoscopic fundoplication compared with medical management in people with GORD that does not respond to optimal proton pump inhibitor (PPI) treatment?

    Recommendation ID CG184/2 Question Laparoscopic fundoplication compared with medical management:- What is the effectiveness of laparoscopic

    Research recommendation
    Published
    9 June 2015

  11. Lifestyle interventions:- How effective and cost effective are different types (and levels and frequency) of physical activity in reducing short- and long-term blood glucose levels and preventing or delaying type 2 diabetes? How does this vary for different subgroups, for example, different black and minority ethnic groups and people of different ages, for example, aged 18–24, 25–39 and 75 and over?

    Recommendation ID PH38/6 Question Lifestyle interventions:- How effective and cost effective are different types (and levels and frequency)

    Research recommendation
    Published
    9 June 2015

  12. What is the effectiveness and safety of sacral nerve stimulation and transanal irrigation compared to symptomatic treatment for people with major low anterior resection syndrome?

    Recommendation ID NG151/2 Question What is the effectiveness and safety of sacral nerve stimulation and transanal irrigation compared to

    Research recommendation
    Published
    10 February 2020

  13. For people with different causes of shoulder pain after stroke, what is the clinical and cost effectiveness of interventions in reducing pain?

    Recommendation ID NG236/5 Question For people with different causes of shoulder pain after stroke, what is the clinical and cost effectiveness

    Research recommendation
    Published
    11 January 2024

  14. Management of smouldering myeloma:- Which combinations of FISH, molecular technologies, bone marrow plasma cell percentage, whole-body imaging, immunophenotype, serum-free light-chain levels or ratio, Hevylite, paraprotein levels, immunoparesis, and International Staging System (ISS) are most effective at risk stratification for people with smouldering myeloma? What is the comparative effectiveness of fixed duration treatment (with or without bone-directed therapy), continuous treatment (with or without bone-directed therapy) and no treatment (with or without bone-directed therapy) for people with smouldering myeloma?

    Recommendation ID NG35/3 Question Management of smouldering myeloma:- Which combinations of FISH, molecular technologies, bone marrow plasma

    Research recommendation
    Published
    5 April 2016

  15. Management of stable angina in people with evidence of ischaemia on non-invasive functional testing:- Do people with stable angina and evidence of reversible ischaemia on noninvasive functional testing who are on optimal drug treatment benefit from routine coronary angiography with a view to revascularisation?

    Recommendation ID CG126/2 Question Management of stable angina in people with evidence of ischaemia on non-invasive functional testing:-

    Research recommendation
    Published
    9 June 2015