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Showing 4216 to 4230 of 7691 results

  1. Additional research could help address uncertainties in the evidence, although the case for cost savings remains unlikely. Although the committee acknowledged that the Game et al. (2018) RCT was well conducted, it felt that additional research could help resolve some uncertainties around the cost and clinical case for 3C Patch. Specifically, research identifying the most appropriate stopping rule, and the associated clinical outcomes of implementing the rule, would help address key uncertainties within the cost case. Additional collection of resource use data on unhealed hard-to-heal ulcers could also reduce uncertainty in the cost case. Further to this, evidence could be collected on an UrgoStart-experienced population, as this would be reflective of current NHS care. Clinical experts thought a trial on this population would be feasible. The committee concluded that although further research could be done, on balance it was unlikely to result in a cost-saving case for 3C Patch based on the decision problem evaluated in this guidance

    Recommendation ID MTG66/01 Question Additional research could help address uncertainties in the evidence, although the case for cost savings

    Research recommendation
    Published
    8 April 2022

  2. ALT values for children and young people:- Further research should be undertaken to examine whether the upper limit of normal ALT values for adults (below 30 IU/ml for males and below 19 IU/ml for females) are appropriate for use in children and young people with chronic hepatitis B when making decisions on when to initiate treatment.

    Recommendation ID CG165/2 Question ALT values for children and young people:- Further research should be undertaken to examine whether

    Research recommendation
    Published
    9 June 2015

  3. Ambulatory oxygen to improve outcomes in idiopathic pulmonary fibrosis:- Does ambulatory oxygen improve outcomes in idiopathic pulmonary fibrosis?

    Recommendation ID CG163/4 Question Ambulatory oxygen to improve outcomes in idiopathic pulmonary fibrosis:- Does ambulatory oxygen improve

    Research recommendation
    Published
    9 June 2015

  4. Amitriptyline to prevent recurrent migraine:- Is amitriptyline a clinically and cost effective prophylactic treatment for recurrent migraine?

    Recommendation ID CG150/1 Question Amitriptyline to prevent recurrent migraine:- Is amitriptyline a clinically and cost effective prophylactic

    Research recommendation
    Published
    9 August 2021

  5. What is the optimal regimen for general anaesthesia for women having surgical abortion?

    Recommendation ID NG140/7 Question What is the optimal regimen for general anaesthesia for women having surgical abortion? Any explanatory

    Research recommendation
    Published
    8 November 2019

  6. What local anaesthetic techniques are most effective for women having surgical abortion?

    Recommendation ID NG140/5 Question What local anaesthetic techniques are most effective for women having surgical abortion? Any

    Research recommendation
    Published
    8 November 2019

  7. Early pregnancy assessment units: A national evaluation of early pregnancy assessment unit service provision should be carried out to identify factors affecting outcomes. Factors should include whether care is provided in a dedicated unit, staffing configuration and opening hours of dedicated services. Outcomes should include both process (service) outcomes and pregnancy-related outcomes. Data collected should be used to analyse the cost effectiveness of early pregnancy assessment units compared with other models of care.

    Recommendation ID NG126/01 Question Early pregnancy assessment units: A national evaluation of early pregnancy assessment unit service

    Research recommendation
    Published
    17 December 2021

  8. Angioplasty versus bypass surgery for treating people with critical limb ischaemia caused by disease of the infra-geniculate arteries:- What is the clinical and cost effectiveness of a 'bypass surgery first' strategy compared with an 'angioplasty first' strategy for treating people with critical limb ischaemia caused by disease of the infra-geniculate (below the knee) arteries?

    Recommendation ID CG147/1 Question Angioplasty versus bypass surgery for treating people with critical limb ischaemia caused by disease

    Research recommendation
    Published
    9 June 2015

  9. What is the optimal antibiotic prophylaxis regimen for women who are having a surgical abortion?

    Recommendation ID NG140/1 Question What is the optimal antibiotic prophylaxis regimen for women who are having a surgical abortion?

    Research recommendation
    Published
    8 November 2019

  10. An instrument to measure quality of life in people with glaucoma:- What instrument should be used to measure health related quality of life in people with glaucoma?

    Recommendation ID NG81/3 Question An instrument to measure quality of life in people with glaucoma:- What instrument should be used to

    Research recommendation
    Published
    18 October 2018

  11. What is the clinical and cost effectiveness of antibiotic prophylaxis to prevent spontaneous bacterial peritonitis (SBP) in people with cirrhosis and ascites?

    Recommendation ID NGO50/2 Question What is the clinical and cost effectiveness of antibiotic prophylaxis to prevent spontaneous bacterial

    Research recommendation
    Published
    11 January 2024

  12. Antibiotic resistance in treating spontaneous bacterial peritonitis:- How frequently does antibiotic resistance occur, and how significant are antibiotic treatment-related complications when antibiotics are used for the primary prevention of spontaneous bacterial peritonitis in people at high risk of having, or developing, cirrhosis?

    Recommendation ID NG50/6 Question Antibiotic resistance in treating spontaneous bacterial peritonitis:- How frequently does antibiotic

    Research recommendation
    Published
    11 January 2024

  13. Antibiotics for suspected early-onset infection: What is the optimal antibiotic dosage regimen for the treatment of early-onset neonatal infection?

    Recommendation ID NG195/12 Question Antibiotics for suspected early-onset infection: What is the optimal antibiotic dosage regimen for

    Research recommendation
    Published
    6 August 2021

  14. What is the effectiveness and safety of anticholinergic medicines for overactive bladder in older women?

    Recommendation ID NG123/1 Question What is the effectiveness and safety of anticholinergic medicines for overactive bladder in older women

    Research recommendation
    Published
    21 June 2019

  15. Anticipatory prescribing:- What is the clinical and cost effectiveness of anticipatory prescribing for patients dying in their usual place of residence, on patient and carer reported symptoms at end of life?

    Recommendation ID NG31/4 Question Anticipatory prescribing:- What is the clinical and cost effectiveness of anticipatory prescribing for

    Research recommendation
    Published
    27 January 2016