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Guidance programme

Advice programme

Showing 4486 to 4500 of 7685 results

  1. What specialist investigations should be conducted to exclude a diagnosis of functional dyspepsia in people with uninvestigated dyspepsia that does not respond to PPIs or H 2   receptor antagonists (H 2 RAs) despite optimum primary care?

    Recommendation ID CG184/5 Question What specialist investigations should be conducted to exclude a diagnosis of functional dyspepsia in

    Research recommendation
    Published
    15 November 2019

  2. Gathering information in schools or nurseries:- Does routine additional information from educational settings (such as nursery or school) improve accuracy in diagnosing autism among children or young people up to the age of 19 compared with signs and symptoms alone?

    Recommendation ID CG128/2 Question Gathering information in schools or nurseries:- Does routine additional information from educational

    Research recommendation
    Published
    9 June 2015

  3. Further research is recommended on clinical outcomes associated with using the ELISA kits (LISA-TRACKER, IDKmonitor and Promonitor) to monitor TNF-alpha-inhibitor levels and antibodies to a TNF-alpha inhibitor in people with Crohn's disease whose disease responds to treatment with TNF-alpha inhibitors. This should be evaluated using prospective studies.

    Recommendation ID DG22/3 Question Further research is recommended on clinical outcomes associated with using the ELISA kits (LISA-TRACKER

    Research recommendation
    Published
    21 March 2016

  4. Further research is recommended on how using sex-specific 99th percentile thresholds affects treatment decisions and clinical outcomes for men and women.

    Recommendation ID DG40/2 Question Further research is recommended on how using sex-specific 99th percentile thresholds affects treatment

    Research recommendation
    Published
    26 October 2020

  5. Further research is recommended on patient acceptability of using virtual chromoendoscopy for real-time assessment of diminutive polyps compared with assessment using histopathology

    Recommendation ID DG28/1 Question Further research is recommended on patient acceptability of using virtual chromoendoscopy for real-time

    Research recommendation
    Published
    12 October 2018

  6. Further research is recommended on resource use and clinical effects associated with using the xTAG Gastrointestinal Pathogen Panel, the FilmArray GI Panel and the Faecal Pathogens B assay.

    Recommendation ID DG26/1 Question Further research is recommended on resource use and clinical effects associated with using the xTAG Gastrointestinal

    Research recommendation
    Published
    17 February 2017

  7. Further research is recommended on: The accuracy of EarlyCDT Lung, and the validity of the risk models used to combine EarlyCDT Lung results with the Brock and the Herder risk models. The impact of EarlyCDT Lung on clinical management decisions. A large retrospective audit is recommended to: Understand how patient and nodule characteristics impact on malignancy prevalence and disease progression. Understand current practice regarding clinical management of people with intermediate-risk lung nodules. Determine the clinical consequences of CT surveillance, including the likelihood of disease progression during CT surveillance. Determine the likelihood and impact of unnecessary biopsy or resection of indolent and benign nodules If existing data on these points is limited or not routinely collected, a prospective data collection should be undertaken to obtain it.

    Recommendation ID DG46/01 Question Further research is recommended on: The accuracy of EarlyCDT Lung, and the validity of the risk models

    Research recommendation
    Published
    24 March 2022

  8. Further research is recommended on the diagnostic performance of the TriageTrue high-sensitivity troponin test using samples at point of care.

    Recommendation ID DG40/1 Question Further research is recommended on the diagnostic performance of the TriageTrue high-sensitivity troponin

    Research recommendation
    Published
    26 October 2020

  9. Further research is recommended on:• the impact of LiverMultiScan test results on decisions about care, such as the decision to do a liver biopsy, or on adherence to lifestyle interventions (see section 3.5 )• the test accuracy of LiverMultiScan compared with biopsy, or the prognostic ability of LiverMultiScan to predict clinical outcomes (see section 3.19 ).

    Recommendation ID DG50/01 Question Further research is recommended on:• the impact of LiverMultiScan test results on decisions about care

    Research recommendation
    Published
    3 February 2023

  10. Further research is recommended on the use of repeat PlGF-based testing (Triage PlGF test and Elecsys immunoassay sFlt-1/PlGF ratio), with standard clinical assessment, in women presenting with suspected pre-eclampsia between 20 weeks and 34 weeks plus 6 days of gestation, who have had a negative PlGF-based test result (Triage PlGF test result of 100 picograms/ml or more; Elecsys immunoassay sFlt 1/PlGF ratio of less than 38) that was used to rule-out pre-eclampsia. This should include:- exploration of the different scenarios in which repeat testing may be indicated- the appropriate intervals between PlGF-based tests- the diagnostic accuracy of PlGF-based testing in women with suspected pre-eclampsia who have previously had 1 or more negative PlGF-based test results.

    Recommendation ID DG23/1 Question Further research is recommended on the use of repeat PlGF-based testing (Triage PlGF test and Elecsys

    Research recommendation
    Published
    22 June 2016

  11. Further research is recommended on:• the impact of magnetic resonance elastography (MRE) test results on decisions about care, such as the decision to do a liver biopsy, or on adherence to lifestyle interventions (see section 3.5 )• the test accuracy of MRE to assess the level of fibrosis or presence of cirrhosis compared with biopsy at thresholds specified by the company, or the prognostic ability of MRE to predict clinical outcomes (see section 3.20 ).

    Recommendation ID DG50/02 Question Further research is recommended on:• the impact of magnetic resonance elastography (MRE) test results

    Research recommendation
    Published
    3 February 2023

  12. Further research is recommended on the use of the Triage PlGF test and Elecsys immunoassay sFlt-1/PlGF ratio, with standard clinical assessment, to rule-in pre-eclampsia in women presenting with suspected pre-eclampsia between 20 weeks and 34 weeks plus 6 days of gestation. This should specifically investigate how a positive PlGF-based test result (Triage PlGF test result of 12 picograms/ml or less; Elecsys immunoassay sFlt 1/PlGF ratio of greater than 38) used to rule-in pre-eclampsia would affect management decisions on time to delivery and the outcomes associated with this.

    Recommendation ID DG23/2 Question Further research is recommended on the use of the Triage PlGF test and Elecsys immunoassay sFlt-1/PlGF

    Research recommendation
    Published
    22 June 2016

  13. Further research is recommended on using ImmunoCAP ISAC 112 for diagnosing allergy and clinical outcomes associated with using allergy testing for people with allergy that is difficult to diagnose, specifically in people with:- idiopathic anaphylaxis- multiple allergies and multiple sensitisations- plant-derived food allergy- seafood allergy, but who have a positive history and negative diagnostic test results.

    Recommendation ID DG24/2 Question Further research is recommended on using ImmunoCAP ISAC 112 for diagnosing allergy and clinical outcomes

    Research recommendation
    Published
    22 June 2016

  14. Further research is recommended to assess:- inter-observer reproducibility of tests involving ultrasound scans (the ADNEX model and Simple Rules)- changes in clinical management based on test results from the ADNEX model, Overa (MIA2G), ROMA and Simple Rules.

    Recommendation ID DG31/2 Question Further research is recommended to assess:- inter-observer reproducibility of tests involving ultrasound

    Research recommendation
    Published
    18 October 2018

  15. Further research is recommended to assess the diagnostic accuracy of the tests included in this assessment when used in combination; for example sequentially.

    Recommendation ID DG31/3 Question Further research is recommended to assess the diagnostic accuracy of the tests included in this assessment

    Research recommendation
    Published
    18 October 2018