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Showing 5686 to 5700 of 7707 results

  1. The Committee recommends that a study estimating utility values using directly observed health-related quality of life values (such as EQ 5D scores) in patients with myelodysplastic syndromes, chronic myelomonocytic leukaemia or acute myeloid leukaemia is conducted.

    Recommendation ID TA218/1 Question The Committee recommends that a study estimating utility values using directly observed health-related

    Research recommendation
    Published
    9 June 2015

  2. The consequences and costs of poor transition:- What are the consequences and the costs of young people with ongoing needs not making a transition into adult services, or being poorly supported through the process?

    Recommendation ID NG43/4 Question The consequences and costs of poor transition:- What are the consequences and the costs of young people

    Research recommendation
    Published
    21 March 2016

  3. In a mild-to-moderate first presentation or inflammatory exacerbation of proctitis that is resistant to standard treatment, what is the effectiveness of topical immunomodulators, such as tacrolimus, in achieving clinical remission and what is the most effective formulation (suppository/ointment)?

    Recommendation ID NG130/1 Question In a mild-to-moderate first presentation or inflammatory exacerbation of proctitis that is resistant

    Research recommendation
    Published
    25 October 2019

  4. The experiences of people with learning disabilities and mental health problems in services:- What experience do people with learning disabilities have of services designed to prevent and treat mental health problems and how does this relate to clinical outcomes?

    Recommendation ID NG54/6 Question The experiences of people with learning disabilities and mental health problems in services:- What experience

    Research recommendation
    Published
    17 October 2016

  5. What is the effectiveness of oral tacrolimus and systemic (intramuscular/subcutaneous/oral) methotrexate in the induction of remission in mild-to-moderate ulcerative colitis unresponsive to aminosalicylates?

    Recommendation ID NG130/2 Question What is the effectiveness of oral tacrolimus and systemic (intramuscular/subcutaneous/oral) methotrexate

    Research recommendation
    Published
    25 October 2019

  6. The frequency and effects of biphasic reactions:- What are the frequency, timing, severity and predictors of biphasic reactions in people who have received emergency treatment for anaphylaxis?

    Recommendation ID CG134/2 Question The frequency and effects of biphasic reactions:- What are the frequency, timing, severity and predictors

    Research recommendation
    Published
    9 June 2015

  7. Home-based antipyretic use: The GDG recommends studies on home-based antipyretic use and parental perception of distress caused by fever. [2013]

    Recommendation ID NG143/05 Question Home-based antipyretic use: The GDG recommends studies on home-based antipyretic use and parental perception

    Research recommendation
    Published
    17 December 2021

  8. The effectiveness of pulsatile gonadotrophin-releasing hormone in women with clomifene citrate-resistant polycystic ovary syndrome is uncertain and is therefore not recommended outside a research context. [2004]

    Recommendation ID CG156/7 Question The effectiveness of pulsatile gonadotrophin-releasing hormone in women with clomifene citrate-resistant

    Research recommendation
    Published
    9 June 2015

  9. Further evidence to address uncertainties about the relative clinical and cost effectiveness of UroLift compared with Rezum, especially in the NHS, would be welcome. This should include: • exploring long-term clinical outcomes and reintervention rates after UroLift • assessing the suitability of UroLift for prostates larger than 80 ml and for those with an obstructive median lobe.

    Recommendation ID MTG58/1 Question Further evidence to address uncertainties about the relative clinical and cost effectiveness of UroLift

    Research recommendation
    Published
    10 August 2021

  10. Management by remote assessment: The GDG recommends that a UK study is undertaken to determine the validity of symptoms reported on remote assessment for children with fever.

    Recommendation ID NG143/02 Question Management by remote assessment: The GDG recommends that a UK study is undertaken to determine the

    Research recommendation
    Published
    17 December 2021

  11. The evidence for treating an acute migraine attack is adequate but, for treating subsequent attacks, is limited in quality and quantity. So, for treating acute migraine, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page . The evidence for preventing migraine is inadequate in quality. So, for preventing migraine, this procedure should only be used in the context of research. Find out what only in research means on the NICE interventional procedures guidance page.

    Recommendation ID IPG740/01 Question The evidence for treating an acute migraine attack is adequate but, for treating subsequent attacks

    Research recommendation
    Published
    7 November 2022

  12. The evidence on efficacy of nerve transfer to partially restore upper limb function in tetraplegia is limited in quantity. There are no major safety concerns. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research.

    Recommendation ID IPG610/1 Question The evidence on efficacy of nerve transfer to partially restore upper limb function in tetraplegia

    Research recommendation
    Published
    21 November 2018

  13. Diagnosis: The GDG recommends that a UK study of the performance characteristics and cost-effectiveness of procalcitonin versus C-reactive protein in identifying serious bacterial infection in children with fever without apparent source be carried out.

    Recommendation ID NG143/03 Question Diagnosis: The GDG recommends that a UK study of the performance characteristics and cost-effectiveness

    Research recommendation
    Published
    17 December 2021

  14. Management according to risk of serious illness: The GDG recommends that research is carried out on referral patterns between primary and secondary care for children with fever, so the health economic impact of this and future guidelines can be estimated.

    Recommendation ID NG143/07 Question Management according to risk of serious illness: The GDG recommends that research is carried out on

    Research recommendation
    Published
    17 December 2021

  15. The evidence on transvaginal laser therapy for stress urinary incontinence does not show any short-term safety concerns. Evidence on long-term safety andefficacy is inadequate in quality and quantity. Therefore, this procedure should only be used in the context of research. Find out what only in research means onthe NICE interventional procedures guidance page.

    Recommendation ID IPG696/1 Question The evidence on transvaginal laser therapy for stress urinary incontinence does not show any short-term

    Research recommendation
    Published
    10 August 2021