Search results

Evidence-based recommendations on pembrolizumab (Keytruda) for treating advanced melanoma in adults who have not had ipilimumab.

Result type

Technology appraisal guidance

Last updated

12 September 2017

Evidence-based recommendations on trastuzumab deruxtecan (Enhertu) for treating HER2-positive unresectable or metastatic breast cancer after 1 or more anti-HER2 treatments in adults.

Result type

Technology appraisal guidance

Published

1 February 2023

Evidence-based recommendations on ivabradine (Procoralan) for treating chronic heart failure in adults.

Result type

Technology appraisal guidance

Published

28 November 2012

Summary of the evidence on domperidone to promote tolerance of enteral feeds in children and young people..

Result type

Evidence summary

Last updated

30 September 2014

This guideline covers diagnosing and treating delirium in people aged 18 and over in hospital and in long-term residential care or a nursing home. It also covers identifying people at risk of developing delirium in these settings and preventing onset. It aims to improve diagnosis of delirium and reduce hospital stays and complications.

Result type

Clinical guideline

Last updated

18 January 2023

This guideline covers how to identify the adults, young people and children with non-alcoholic fatty liver disease (NAFLD) who have advanced liver fibrosis and are most at risk of further complications. It outlines the lifestyle changes and pharmacological treatments that can manage NAFLD and advanced liver fibrosis.

Result type

NICE guideline

Published

6 July 2016

Evidence-based recommendations on daratumumab (Darzalex) with lenalidomide and dexamethasone for untreated multiple myeloma in adults, when a stem cell transplant is unsuitable.

Result type

Technology appraisal guidance

Published

25 October 2023

Evidence-based recommendations on imlifidase (Idefirix) for desensitisation treatment before kidney transplant in people with chronic kidney disease.

Result type

Technology appraisal guidance

Published

20 July 2022

Evidence-based recommendations on drainage, irrigation and fibrinolytic therapy (DRIFT) for post-haemorrhagic hydrocephalus in preterm infants. This involves draining excess CSF from the brain, washing out the blood, and breaking down blood clots using drugs (fibrinolytics).

Result type

Interventional procedures guidance

Published

23 November 2011

Evidence-based recommendations on balloon dilatation of systemic to pulmonary arterial shunts in children. This involves inflating a balloon inserted into the area so blood can flow through more easily.

Result type

Interventional procedures guidance

Published

28 July 2004

Evidence-based recommendations on rituximab for untreated chronic lymphocytic leukaemia in adults.

Result type

Technology appraisal guidance

Published

22 July 2009

Evidence-based recommendations on extracorporeal membrane oxygenation for severe acute respiratory failure in adults. This involves using a tube to carry blood from the right side of the heart and then pump it through an artificial lung where it picks up oxygen.

Result type

Interventional procedures guidance

Published

27 April 2011

Evidence-based recommendations on irreversible electroporation for treating pancreatic cancer. This involves inserting special needles into the tumour in the pancreas and using short electrical pulses to destroy the cancer cells.

Result type

Interventional procedures guidance

Published

3 May 2017

Evidence-based recommendations on percutaneous closure of the patent foramen ovale for the prevention of cerebral embolic stroke. This involves placing a small device into the heart to close the hole.

Result type

Interventional procedures guidance

Published

18 December 2013

This quality standard covers assessing, diagnosing and referring people (aged 16 and over) who have had a transient loss of consciousness (often called a blackout). It describes high-quality care in priority areas for improvement.

Result type

Quality standard

Published

2 October 2014