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This advice has been withdrawn because Novartis has discontinued ofatumumab (Arzerra). Ofatumumab will continue to be available for people who need it. Contact Clinigen at managedacess@clinigengroup.com or 01932 842100 for details.
Eluxadoline for treating irritable bowel syndrome with diarrhoea (TA471)
We have withdrawn this guidance. Allergan has stopped marketing eluxadoline (Truberzi) for commercial reasons and its marketing authorisation has been withdrawn.
Obinutuzumab with bendamustine for treating follicular lymphoma refractory to rituximab (TA472)
This guidance has been updated and replaced by NICE technology appraisal guidance 629.
This guidance has been updated and replaced by NICE guideline NG107
This guidance has been replaced by NICE technology appraisal guidance 71.
The clinical effectiveness and cost effectiveness of infliximab for Crohn's disease (TA40)
This guidance has been updated and replaced by NICE technology appraisal guidance 187.
This guidance has been updated and replaced by NICE guideline CG82.
Mepolizumab for treating severe refractory eosinophilic asthma (TA431)
This technology appraisal guidance has been updated and replaced by NICE technology appraisal guidance 671.
Belimumab for treating active autoantibody-positive systemic lupus erythematosus (TA397)
This guidance has been updated and replaced by NICE technology appraisal guidance 752.
This technology appraisal guidance has been updated and replaced by NICE technology appraisal guidance 657
Collagenase clostridium histolyticum for treating Dupuytren's contracture (TA459)
We have withdrawn the guidance because collagenase clostridium histolyticum (Xiapex) is no longer available in the UK.
Guidance on the use of metal on metal hip resurfacing arthroplasty (TA44)
This guidance has been updated and replaced by NICE technology appraisal guidance 304.
Daclizumab for treating relapsing–remitting multiple sclerosis (TA441)
This guidance has been withdrawn because Biogen is withdrawing its marketing authorisations for daclizumab. See the European Medicines Agency’s advice on daclizumab.
This technology appraisal guidance has been updated and replaced by NICE technology appraisal guidance 674. People already taking pembrolizumab for untreated PD-L1-positive locally advanced or metastatic urothelial cancer when cisplatin is unsuitable through the Cancer Drugs Fund can continue. For those people, it will be funded by the company until they and their doctor decide when best to stop.
Computerised cognitive behaviour therapy (CCBT) for the treatment of depression and anxiety (TA51)
This guidance has been updated and replaced by NICE technology appraisal guidance 97.