Search results

Evidence-based recommendations on Barnett Continent Intestinal Reservoir (modified continent ileostomy) to restore continence after colon and rectum removal in adults. This involves using the ileum to create a pouch on the inside of the abdominal wall to collect waste.

Result type

HealthTech guidance

Published

20 February 2019

Evidence-based recommendations on ex-situ machine perfusion for extracorporeal preservation of livers for transplantation in people of all ages. This involves using a machine to give an oxygenated solution to the donor liver until it is transplanted.

Result type

HealthTech guidance

Published

16 January 2019

Evidence-based recommendations on percutaneous insertion of a temporary heart pump for left ventricular haemodynamic support in high-risk percutaneous coronary interventions. This involves inserting temporary pump to support circulation during a heart operation.

Result type

HealthTech guidance

Published

28 November 2018

Evidence-based recommendations on ultrasound-guided high-intensity transcutaneous focused ultrasound for symptomatic uterine fibroids in adults. This involves focusing high-intensity ultrasound energy at the fibroids through the skin of the abdomen.

Result type

HealthTech guidance

Published

24 July 2019

Evidence-based recommendations on laparoscopic ventral mesh rectopexy for internal rectal prolapse in adults. This involves using a piece of sterile material (mesh) to attach the rectum to the lower back bone using keyhole surgery.

Result type

HealthTech guidance

Published

20 June 2018

Evidence-based recommendations on unilateral MRI-guided focused ultrasound thalamotomy for treatment-resistant essential tremor in adults. This involves applying ultrasound to a specific area on 1 side of the brain (thalamus).

Result type

HealthTech guidance

Published

20 June 2018

Evidence-based recommendations on azacitidine (Vidaza) for treating myelodysplastic syndromes, chronic myelomonocytic leukaemia and acute myeloid leukaemia in adults.

Result type

Technology appraisal guidance

Published

23 March 2011

Late-stage assessment (LSA) guidance on drug-eluting stents for treating coronary artery disease.

Result type

HealthTech guidance

Published

6 May 2025

This integrated process statement has been produced to explain how 'Evidence summaries: unlicensed and off-label medicines' (ESUOMs) are developed. It provides an overview of the key process principles and describes all stages of development for ESUOMs

Evidence-based recommendations on vutrisiran (Amvuttra) for wild-type or hereditary transthyretin amyloidosis with cardiomyopathy in adults.

Result type

Technology appraisal guidance

Published

10 December 2025

This document describes a real-world evidence framework that aims to improve the quality of real-world evidence informing our guidance. The framework does not set minimum standards for the acceptability of evidence. The framework is mainly targeted at those developing evidence to inform NICE guidance. It is also relevant to patients, those collecting data, and reviewers of evidence

Evidence-based recommendations on daridorexant (QUVIVIQ) for treating long-term insomnia in adults.

Result type

Technology appraisal guidance

Published

18 October 2023

Evidence-based recommendations on mini/micro screw implantation for orthodontic anchorage. This involves inserting small screws into the jaw bone to create anchors that support tooth realignment.

Result type

HealthTech guidance

Published

28 November 2007

Evidence-based recommendations on avelumab (Bavencio) for metastatic Merkel cell carcinoma in adults.

Result type

Technology appraisal guidance

Last updated

21 April 2021

Evidence-based recommendations on axicabtagene ciloleucel (Yescarta) for treating relapsed or refractory diffuse large B-cell lymphoma after first-line chemoimmunotherapy.

Result type

Technology appraisal guidance

Published

7 June 2023