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Showing 1441 to 1455 of 2188 results for guidelines

  1. Delirium in long-term care: How common is delirium and what are its adverse outcomes in people in long-term care?

    potential significant risk factors and confounding factors identified in the guideline. Such a study would also inform...

    Research recommendation
    Published
    3 February 2023

  2. Physiotherapy:- Does physiotherapy started early in the course of Parkinson's disease, as opposed to after motor symptom onset, confer benefits in terms of delaying symptom onset and/or reducing severity?

    Any explanatory notes(if applicable) Why this is important:- The guideline committee felt that physiotherapy was beneficial for those...

    Research recommendation
    Published
    15 October 2018

  3. Robot-assisted surgery for soft tissue procedures: early value assessment (HTG742)

    Early value assessment (EVA) guidance on robot-assisted surgery for soft tissue procedures.

    HealthTech guidance
    Published
    17 April 2025
    View recommendations

    Sections for HTG742

  4. Axicabtagene ciloleucel for treating relapsed or refractory diffuse large B-cell lymphoma after first-line chemoimmunotherapy (TA895)

    Evidence-based recommendations on axicabtagene ciloleucel (Yescarta) for treating relapsed or refractory diffuse large B-cell lymphoma after first-line chemoimmunotherapy.

    Technology appraisal guidance
    Published
    7 June 2023
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    Sections for TA895

  5. Tildrakizumab for treating moderate to severe plaque psoriasis (TA575)

    Evidence-based recommendations on tildrakizumab (Ilumetri) for treating moderate to severe plaque psoriasis in adults.

    Technology appraisal guidance
    Published
    17 April 2019
    View recommendations

    Sections for TA575

  6. Tirzepatide for treating type 2 diabetes (TA924)

    Evidence-based recommendations on tirzepatide (Mounjaro) for type 2 diabetes in adults.

    Technology appraisal guidance
    Last updated
    1 September 2025
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    Sections for TA924

  7. Tucatinib with trastuzumab and capecitabine for treating HER2-positive advanced breast cancer after 2 or more anti-HER2 therapies (TA786)

    Evidence-based recommendations on tucatinib (TUKYSA) for HER2-positive locally advanced or metastatic breast cancer in adults after 2 or more anti-HER2 treatment therapies.

    Technology appraisal guidance
    Published
    27 April 2022
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    Sections for TA786

  8. Genedrive MT-RNR1 ID Kit for detecting a genetic variant to guide antibiotic use and prevent hearing loss in babies: early value assessment (HTG665)

    Early value assessment (EVA) guidance on the Genedrive MT-RNR1 ID Kit for detecting a genetic variant to guide antibiotic use and prevent hearing loss in babies.

    HealthTech guidance
    Last updated
    10 August 2023
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    Sections for HTG665

  9. Indwelling urinary catheters: catheter selection:- For patients using a long-term indwelling urinary catheter, what is the clinical and cost effectiveness of impregnated versus hydrophilic versus silicone catheters in reducing symptomatic urinary tract infections, encrustations and/or blockages?

    catheters, but are also more expensive. The clinical evidence review for the guideline revealed an absence of evidence for the...

    Research recommendation
    Published
    9 June 2015

  10. Intrathecal baclofen:- What is the clinical and cost effectiveness of continuous pump-administered intrathecal baclofen compared with usual care in children and young people who are at Gross Motor Function Classification System (GMFCS) level IV or V?

    Any explanatory notes(if applicable) Why this is important:- The Guideline Development Group's (GDG's) recommendation to consider...

    Research recommendation
    Published
    9 June 2015

  11. Sapropterin for treating hyperphenylalaninaemia in phenylketonuria (TA729)

    Evidence-based recommendations on sapropterin for treating hyperphenylalaninaemia in phenylketonuria.

    Technology appraisal guidance
    Published
    22 September 2021
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    Sections for TA729

  12. Avoidance of aspiration pneumonia: Does the withdrawal of oral liquids or the use of modified (thickened) oral fluids prevent the development of aspiration pneumonia after an acute stroke?

    after an acute stroke are at higher risk of aspiration pneumonia. The guideline development group considered how best to reduce the...

    Research recommendation
    Published
    11 May 2022

  13. Switching from inpatient intravenous to outpatient oral antibiotic therapy in patients with neutropenic sepsis:- A randomised controlled trial should be undertaken to evaluate the clinical and cost effectiveness of stopping intravenous antibiotic therapy and switching to oral therapy within the first 24 hours of treatment in patients with neutropenic sepsis who are having treatment with intravenous antibiotics. The outcomes to be measured are overtreatment, death, need for critical care, length of hospital stay, duration of fever and quality of life.

    treatment at a variety of time points. A meta-regression undertaken by the Guideline Development Group suggested that very early (before...

    Research recommendation
    Published
    9 June 2015

  14. Targeted interventions to support and improve decision-making capacity for treatment:- What is the effectiveness and cost effectiveness of different targeted interventions (speech and language therapy and psychological and psychosocial interventions) to support and improve decision-making capacity for treatment in specific groups?

    the studies were limited in number and generally of low quality. The guideline committee agreed that further research in this area...

    Research recommendation
    Published
    18 December 2018

  15. Radiofrequency denervation:- What is the clinical and cost effectiveness of radiofrequency denervation for chronic low back pain in the long term?

    unreasonable clinical expectation. The economic model presented in this guideline suggested that radiofrequency denervation is likely to...

    Research recommendation
    Published
    13 February 2017