Past appeals

TA IDAppraisal short titleAppeal hearing date
TBC Afamelanotide for erythropoietic protoporphyria [ID927] 15 May 2023
TA721 Abiraterone for treating newly diagnosed high risk metastatic hormone-naive prostate cancer [ID945] 3 September 2020
TBC Afamelanotide for treating erythropoietic protoporphyria 30 July 2018
TA111 Alzheimer´s disease - donepezil, rivastigmine, galantamine and memantine (review) 13-14 August 2006
TA142 Anaemia (cancer-treatment induced) - Erythropoetin (alpha and beta) and darbepoetin 2 June 2006
TA143 Ankylosing spondylitis - adalimumab, etanercept & infliximab 31 March 2008
TA010 Asthma (children under 5) - inhaler devices 31 August 2000
TA138 Asthma (in adults) - corticosteroids 9 January 2008
TA038 Asthma (older children) - inhaler devices 13 February 2002
TA249 Atrial fibrillation - dabigatran etexilate 7 February 2012
TA098 Attention deficit hyperactivity disorder - Methylphenidate, atomoxetine and dexamfetamine (review) 25 September 2005
ID3735 Avelumab for maintenance treatment of locally advanced or metastatic urothelial cancer after platinum-based chemotherapy 28 September 2021
TA926 Baricitinib for treating severe alopecia areata 12 September 2023
TA006 Breast cancer - taxanes 3 May 2000
TA054 Breast cancer - vinorelbine 15 August 2002
TBC Breast cancer (advanced or metastatic) - lapatinib 8 June 2009
TBC Breast cancer (advanced or metastatic) - lapatinib (second appeal) 17 August 2010
TA107 Breast cancer (early) - trastuzumab 26 July 2006
TA257 Breast cancer (metastatic hormone-receptor) - lapatinib and trastuzumab (with aromatase inhibitor): appeal 23 May 2011
TA006 Breast cancer - taxanes 14 June 2000
TA250 Breast cancer - eribulin 13 February 2012
TA350 Breast cancer (HER2 positive, unresectable) - trastuzumab emtansine (after trastuzumab & taxane) 13 October 2014
TA928 Cabozantinib for previously treated advanced differentiated thyroid cancer unsuitable for or refractory to radioactive iodine 19 September 2023
TA033 Colorectal cancer - Irinotecan, oxaliplatin and raltitrexed 23 May 2001
TA033 Colorectal cancer (advanced) - irinotecan, oxaliplatin and raltitrexed 8 January 2002
TA307 Colorectal cancer (metastatic) – aflibercept  23 January 2014
TA118 Colorectal cancer (metastatic) - bevacizumab & cetuximab 27 November 2006
TA102 Conduct disorder in children - parent-training/education programmes 21 April 2006
TA152 Coronary artery stents - drug-eluting stents 14 April 2008
TA051 Depression and anxiety - computerised cognitive behaviour therapy (CCBT) 19 July 2002
TA097 Depression and anxiety - computerised cognitive behavioural therapy (CCBT)(review) 17 November 2005
TA151 (review TA57) Diabetes - insulin pump therapy (review) 16 May 2008
TA063 Diabetes (Type 2) - glitazones (review) 2 June 2003
TA459 Dupuytren's contracture - collagenase clostridium histolyticum 30 November 2015
TA007 Dyspepsia - proton pump inhibitors 29 June 2000
TA059 Electroconvulsive Therapy (ECT) 12 February 2003
TA076 Epilepsy (adults) - newer drugs 19 January 2004
TBC Erenumab for treating migraine 4 December 2019
TA854 Esketamine for treatment-resistant depression [ID1414] 27 July 2022
TA067 Flu (prophylaxis) - amantadine and oseltamivir 19 December 2002
TA759 Fostamatinib for treating persistent or chronic immune thrombocytopenia [ID1087] 9 November 2021
TA064 Growth hormone deficiency (adults) - human growth hormone 20 August 2002
TA064 Growth hormone deficiency (adults) - human growth hormone 3 July 2003
TA145 Head and neck cancer - cetuximab 22 August 2007
TA008 Hearing disability - hearing aids 21 July 2000
TA166 Hearing impairment - cochlear implants 26 November 2008
TA189 Hepatocellular carcinoma (advanced and metastatic)- sorafenib 26 February 2010
TA018 Hernia (inguinal) - laparoscopic surgery 7 December 2000
TA002 Hip disease - replacement prostheses 31 March 2000
TA164 Hyperuricaemia - febuxostat 29 October 2008
TA504 Idiopathic pulmonary fibrosis - pirfenidone 2 December 2016,
and 1 December 2017
TA501 Intrabeam radiotherapy system for adjuvant treatment of early breast cancer 8 December 2017
TA482 Kidney transplantation (adults) - immunosuppressive therapy (review) 30 March 2016
TA482 Kidney transplantation (children, adolescents) - immunosuppressive regimens (review) 30 March 2016
TA541 Leukaemia (acute lymphoblastic, relapsed, adults) - inotuzumab ozogamicen 3 November 2017
TA193 Leukaemia (chronic lymphocytic, relapsed) - rituximab 25 May 2010
TA251 Leukaemia (chronic myeloid) - dastatinib, nilotinib, imatinib (intolerant, resistant) (including partial review of TA70) 4 November 2011
TA162 Lung cancer (non-small cell) - Erlotonib 6 June 2007
TA227 Lung cancer (non-small-cell, advanced or metastatic maintenance treatment) - erlotinib: appeal 16 May 2011
TA124 Lung cancer (non-small cell) - pemetrexed 6 June 2007
TBC Lysosomal acid lipase deficiency - sebelipase alfa 25 April 2017
TA068 Macular degeneration (age-related) - photodynamic therapy 17 March 2003
TA155 Macular degeneration (age-related) - ranibizumab and pegaptanib 30 June 2008
TA237 Macular oedema (diabetic) - ranibizumab: appeal 4 October 2011
TA078 Menorrhagia - endometrial ablation 26 January 2004
TA135 Mesothelioma - Pemetrexed disodium 27 October 2006
TA754 Mogamulizumab for previously treated mycosis fungoides and Sézary syndrome [ID1405] 11 May 2021
TA020 Motor neurone disease - riluzole 4 January 2001
TA129 Multiple myeloma - Bortezomib 8 February 2007
TA228 Multiple myeloma (first line) - bortezomib and thalidomide 15 November 2010
TA032 Multiple sclerosis - beta interferon and glatiramer 22-23 September 2000
TA032 Multiple sclerosis - beta interferon and glatiramer acetate 26 November 2001
TA218 Myelodysplastic syndrome - azacitidine 1 June 2010
TBC Neuroblastoma (high-risk) - dinutuximab (maintenance, after therapy) 30 September 2016
TA494 Obesity (prolonged-release) - naltrexone-bupropion 12 December 2017
ID3913 Olipudase alfa for treating Niemann-Pick disease types A and B 24 May 2024
TA621 Osimertinib for untreated EGFR-positive non-small-cell lung cancer 30 September 2019
TA027 Osteoarthritis and rheumatoid arthritis - cox II inhibitors 7 June 2001
TA160 Osteoporosis - primary prevention 22 October 2007
TA160 Osteoporosis - primary prevention 15 September 2008
TA087 Osteoporosis - secondary prevention 22 October 2004
TA161 Osteoporosis - secondary prevention including strontium ranelate 22 October 2007
TA161 Osteoporosis - secondary prevention including strontium ranelate 15 September 2008
TA055 Ovarian cancer - paclitaxel (review) 12 November 2002
TA389 Ovarian cancer - topotecan, pegylated liposomal doxorubicin hydrochloride, paclitaxel, trabectedin and gemcitabine for advanced recurrent disease only (Review of TA 91 & TA 222) [ID468] 24 April 2015
TA360 Pancreatic adenocarcinoma (Metastatic) paclitaxel albumin-bound nanoparticles (with gemcitabine, 1st line) [ID680] 16 March 2015
TBC Pembrolizumab for treating locally advanced or metastatic urothelial carcinoma after platinum-containing chemotherapy [ID1536] 23 June 2020
TA135 Pemetrexed disodium for the treatment of malignant pleural mesothelioma (2) 23 November 2007
TA103 Psoriasis - efalizumab and etanercept 27 January 2006
TA104 Psoriatic arthritis - etanercept and infliximab 20 February 2006
TA104 Psoriatic arthritis (active) - apremilast (after-DMARDs) 6 November 2015
TA255 Prostate cancer - cabazitaxel 22 March 2012
TA352 Prostate cancer (advanced, hormone dependent) - degarelix depot [ID590] 12 November 2014
TA832 Relugolix–estradiol–norethisterone acetate for treating moderate to severe symptoms of uterine fibroids [ID3842] 7 September 2022
TA178 Renal cell carcinoma - bevacizumab, sorafenib, sunitinib and temsirolimus 13 July 2009
TA333 Renal cell carcinoma, locally advanced and/or metastatic (2nd line) - axitinib [ID518] 10 June 2013
TA219 Renal cell carcinoma (second line metastatic) - everolimus 28 February 2011
TA085 Renal transplantation - immuno-suppressive regimens (adults) 26 April 2004
TA130 Rheumatoid arthritis - Adalimumab, etanercept and infliximab 4 April 2007
TA072 Rheumatoid arthritis - anakinra 18 September 2003
TA375 Rheumatoid arthritis - adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, abatacept and tocilizumab - review [ID537] 26 November 2015
TA141 Rheumatoid arthritis (refractory) - abatacept 17 March 2008
TA037 Rituximab for follicular lymphoma 21 May 2001
TA043 Schizophrenia - Atypical antipsychotic 24 April 2002
TA397 Systemic lupus erythematosus (active) - belimumab 18 July 2012
TA696 Tafamidis for treating transthyretin amyloid cardiomyopathy 4-5 March 2021
TBC Tafasitamab with lenalidomide for treating relapsed or refractory diffuse large B-cell lymphoma [ID3795] 14 November 2022
TA272 Transitional cell carcinoma of the urothelial tract - vinflunine 23 May 2011
TA090 Vascular disease - clopidogrel and dipyridamole 25 February 2005

Back to top

Rejected appeals

TA IDAppraisal Short title
TA201 Asthma (in children) - omalizumab
TA265 Bone metastases from solid tumours - denosumab
TA566 Cochlear implant for children and adults with severe to profound deafness (Part review of TA166) [ID1469]
TA209 Gastrointestinal stromal tumours (unresectable/metastatic) - imatinib (review)
TA510 Multiple myeloma (relapsed, refractory) - daratumumab (after proteasome inhibitor and immunomodulatory agent)
GID-HST10008 Neuronal ceroid lipofuscinosis type 2 - cerliponase alfa (Biomarin) [ID943]
TA316 Prostate cancer (hormone relapsed, metastatic) - enzalutamide (after docetaxel)
TA272 Urothelial tract carcinoma (transitional cell, advanced, metastatic) - vinflunine

Back to top

Cancelled appeals

TA IDAppraisal short title
TA383 Ankylosing spondylitis and axial spondyloarthritis (non-radiographic) - adalimumab, certolizumab pegol, etanercept, golimumab and infliximab (inc rev TA143 and TA233) ID694
HST6

Hypophosphatasia (paediatric-onset) - asfotase alfa

TA10812 Lorlatinib for untreated ALK-positive advanced non-small-cell lung cancer [ID3896]
TA309 Lung cancer (non small cell, non squamous) - pemetrexed (maintenance following pemetrexed & cisplatin)
TBC Metreleptin for treating lipodystrophy
TBC Non-small cell lung cancer (non-squamous) - nivolumab (CDF review TA484) [ID1572]

Back to top