Chronic urticaria: off-label doses of cetirizine

What is chronic urticaria?

Urticaria is a raised, itchy skin rash. When the rash lasts for more than 6 weeks or when it keeps coming back, it is known as chronic urticaria. Chronic urticaria can last for months or years. Often the cause is not known, but it may be triggered by a virus, stress or medicines.

If possible, the cause of urticaria should be identified and managed. People who need treatment are usually offered an antihistamine. This should be one that doesn't cause drowsiness at the standard dose. In some people, symptoms don't improve with this treatment. When this happens it is common practice to increase the dose of antihistamine if the benefits are likely to outweigh the risks.