pCONUS2 Bifurcation Aneurysm Implant for complex intracranial aneurysms

The technology described in this briefing is the pCONUS2 Bifurcation Aneurysm Implant. It is used for assisting in the coil occlusion of wide-necked aneurysms that span the division of an artery into 2 branches.

The innovative aspects are that the implant has a less than 5% metal to artery surface ratio and can be used without dual antiplatelet treatment.

The intended place in therapy would be as an alternative to standard care in people with complex intracranial aneurysms.

The main points from the evidence summarised in this briefing are from 1 case series study including a total of 12 adults in secondary care. They show that pCONUS2 is safe and effective at assisting the coil occlusion of an intracranial aneurysm.

Key uncertainties around the evidence or technology are that the evidence is from a case series of only 12 patients. There are no comparative studies evaluating its efficacy against standard care.

The cost of pCONUS2 is £6,760.00 per unit (excluding VAT), or £7,774.00 per unit with the hydropolymer coating (excluding VAT).