Butterfly iQ+ for diagnostic ultrasound imaging

The technology described in this briefing is the Butterfly iQ+. It is used for external diagnostic ultrasound imaging in adults and children.

The innovative aspects are that it is the first handheld device that can be used for multiple applications, with a single probe emulating different probe types. It is powered by a single silicon chip, 'ultrasound on a chip', and connected to a smartphone. It could be used in settings where there is no access to alternative ultrasound equipment.

The intended place in therapy would be as an alternative to point‑of‑care ultrasound devices for people who need diagnostic ultrasound imaging.

The main points from the evidence summarised in this briefing are from 5 observational studies including 174 people. They show that the Butterfly iQ+ can be effective as a diagnostic ultrasound tool across a variety of indications.

Key uncertainties around the technology are that experts expressed concerns about image quality and size on a smartphone screen. Key uncertainties around the evidence are that there were only 2 comparative studies, and these did not report patient outcomes. Also, only 1 study was done in the UK.

The cost of Butterfly iQ+ is £1,699 per unit, plus £360 per year as a membership fee (excluding VAT). Standard care costs between £6,000 and £19,500 for point‑of‑care ultrasound devices and between £30,000 and £100,000 for traditional cart‑based ultrasound devices.