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Faecal microbiota transplant for recurrent Clostridioides difficile infection

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1 Recommendations

1.1 Faecal microbiota transplant (FMT) is recommended as a cost saving option to treat recurrent Clostridioides difficile infection in adults who have had 2 or more previous episodes.

Why the committee made these recommendations

Clinical trial evidence shows that FMT is significantly better than antibiotics at resolving a C. difficile infection in people who have had 2 or more previous infections.

FMT is cheaper than all treatment with antibiotics, regardless of how it is delivered. It is cost saving by at least £1,500 per person.