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2 Information about fedratinib

Marketing authorisation indication

2.1 Fedratinib (Inrebic, Celgene) has a marketing authorisation for 'the treatment of disease-related splenomegaly or symptoms in adult patients with primary myelofibrosis, post polycythaemia vera myelofibrosis or post essential thrombocythaemia myelofibrosis who are Janus Associated Kinase (JAK) inhibitor naive or have been treated with ruxolitinib'.

Price

2.3 The list price of fedratinib is £6,120 for a 120‑capsule pack of 100 mg capsules (excluding VAT, company submission). The company has a commercial arrangement, which would have applied if the technology had been recommended.