Contents

Introduction

Description of the procedure

Safety summary

References

Abbreviations

Word or phrase	Abbreviation
Adverse Event	AE
Anterior posterior	AP
Brachytherapy	BT
Confidence Interval	CI
3-dimensional conformal radiation therapy	3D-CRT
External beam radiotherapy	EBRT
Expanded Prostate Cancer Index Composite	EPIC
Endorectal balloon	ERB
Fraction	fx
Gastrointestinal	GI
Genitourinary	GU
Grading of Recommendations, Assessment, Development and Evaluation	GRADE
Hazard Ratio	HR
High dose rate brachytherapy	HDR BT
Health technology assessment	HTA
Image-guided intensity modulated radiotherapy	IG-IMRT
Intensity modulated proton therapy	IMPT
Low dose rate brachytherapy	LDR BT
Manufacturer and User Facility Device Experience	MAUDE
Mean difference	MD
Minimally Important Difference	MID
Non-randomised Control Trial	nRCT
National Cancer Institute Common Terminology Criteria for Adverse Events	NCICTCAE
Not available	NA
Not estimated	NE
Not reported	NR
Not significant	NS
Odds ratio	OR
Proton beam therapy	PBT
Preferred Reporting Items for Systematic reviews and Meta-Analyses	PRISMA
Quality of life	QoL
Randomised Control Trial	RCT
Radiotherapy	RT
Radiation Therapy Oncology Group	RTOG
Risk difference	RD
Relative Risk	RR
Radiotherapy	RT
Reduction in rectal volume of dose of, for example 50Gy	rV
Stereotactic body radiation therapy	SBRT
Standard deviation	SD
Superior-inferior	SI
Volumetric modulated arc radiotherapy	VMAT
Vienna Rectoscopy scores	VRS

Interventional procedure overview of biodegradable spacer insertion to reduce rectal toxicity during radiotherapy for prostate cancer