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    Literature search strategy

    Databases

    Date searched

    Version/files

    Cochrane Database of Systematic Reviews – CDSR (Cochrane Library)

    29/09/2021

    Issue 9 of 12, September 2021

    Cochrane Central Database of Controlled Trials – CENTRAL (Cochrane Library)

    29/09/2021

    Issue 9 of 12, September 2021

    International HTA database

    29/09/2021

    -

    MEDLINE (Ovid)

    29/09/2021

    1946 to September 27, 2021

    MEDLINE In-Process (Ovid) & MEDLINE ePubs ahead of print (Ovid)

    29/09/2021

    1946 to September 27, 2021

    EMBASE (Ovid)

    29/09/2021

    1974 to 2021 September 27

    Embase Conference (Ovid)

    29/09/2021

    1974 to 2021 September 27

    Trial sources searched November 2020

    • Clinicaltrials.gov

    • ISRCTN

    • WHO International Clinical Trials Registry

    Websites searched November 2020

    • National Institute for Health and Care Excellence (NICE)

    • NHS England

    • Food and Drug Administration (FDA) - MAUDE database

    • Australian Safety and Efficacy Register of New Interventional Procedures – Surgical (ASERNIP – S)

    • Australia and New Zealand Horizon Scanning Network (ANZHSN)

    • General internet search

    MEDLINE search strategy

    The MEDLINE search strategy was translated for use in the other sources.

    Strategy used:

    1 ((chondral or osteochondral or chondrocyt* or chondroblast* or osteochondriti*) adj4 (defect* or damag* or injur* or lesion*)).tw.

    2 ((knee* or patella* or trochlea* or cartilage or chondrocyte* or condyle* or chondropath*) adj4 (defect* or damag* or injur* or lesion* or osteoarthritis or disease*)).tw.

    3 Knee Injuries/

    4 Osteochondritis/

    5 exp Cartilage Diseases/

    6 Osteoarthritis, Knee/

    7 or/1-6

    8 (inlay adj4 resurfac* adj4 prosthesis).tw.

    9 ((focal* or femoral*) adj4 (implant* or resurfac* or replac*)).tw.

    10 (knee* adj4 resurfac*).tw.

    11 Knee Joint/

    12 "Prostheses and Implants"/

    13 11 and 12

    14 8 or 9 or 10 or 13

    15 7 and 14

    16 HemiCAP.tw.

    17 UniCAP.tw.

    18 Episealer.tw.

    19 Biopoly.tw.

    20 or/16-19

    21 15 or 20

    22 limit 21 to english language

    23 Animals/ not Humans/

    24 22 not 23