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    Literature search strategy

    Databases

    Date searched

    Version/files

    Cochrane Database of Systematic Reviews – CDSR (Cochrane Library)

    29/11/2021

    Issue 11 of 12, November 2021

    Cochrane Central Database of Controlled Trials – CENTRAL (Cochrane Library)

    29/11/2021

    Issue 11 of 12, November 2021

    International HTA database

    29/11/2021

    -

    MEDLINE (Ovid)

    29/11/2021

    1946 to November 24, 2021

    MEDLINE In-Process (Ovid) & MEDLINE ePubs ahead of print (Ovid)

    29/11/2021

    1946 to November 24, 2021

    EMBASE (Ovid)

    29/11/2021

    1974 to 2021 November 24

    Embase Conference (Ovid)

    29/11/2021

    1974 to 2021 November 24

    Trial sources searched

    • Clinicaltrials.gov

    • ISRCTN

    • WHO International Clinical Trials Registry

    Websites searched

    • National Institute for Health and Care Excellence (NICE)

    • NHS England

    • Food and Drug Administration (FDA) - MAUDE database

    • Australian Safety and Efficacy Register of New Interventional Procedures – Surgical (ASERNIP – S)

    • Australia and New Zealand Horizon Scanning Network (ANZHSN)

    • General internet search

    MEDLINE search strategy

    The MEDLINE search strategy was translated for use in the other sources.

    1 Glaucoma, Open-Angle/

    2 ((Primary or second* or refract* or compensat*) adj4 open angle glaucoma*).tw.

    3 (POAG or COAG).tw.

    4 Ocular Hypertension/

    5 Intraocular Pressure/

    6 IOP.tw.

    7 ((Ocular* or intraocul* or eye) adj4 (hypertens* or pressure*)).tw.

    8 (open adj4 angle* adj4 glaucoma*).tw.

    9 Pseudo-exfoliative glaucoma.tw.

    10 Pigment* glaucoma*.tw.

    11 (simpl* adj4 glaucoma).tw.

    12 or/1-11

    13 ab interno.tw.

    14 canaloplast*.tw.

    15 ABiC.tw.

    16 (circumferent* adj4 viscodilat*).tw.

    17 or/13-16

    18 12 and 17

    19 iTrack.tw.

    20 18 or 19

    21 Animals/ not Humans/

    22 20 not 21