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    Interventional procedure overview of radiofrequency ablation as an adjunct to balloon kyphoplasty or percutaneous vertebroplasty for palliation of painful spinal metastases

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    A prospective observational study of 65 patients with painful spinal metastases in the thoracolumbar spine (T1-L5) following targeted radiofrequency ablation (t-RFA) treatment with the STAR™ Tumor Ablation System, follow up 12 months, outcome measures are pain relief and quality of life improvement; location USA, study completion date March 2017; status: study was terminated due to difficulty enrolling.References

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    2. Rosian K, Hawlik K and Piso B (2018). Efficacy assessment of radiofrequency ablation as a palliative pain treatment in patients with painful metastatic spinal lesions: A systematic review. Pain Physician 2018; 21: E467-E476.

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    4. Greif DN, Ghasem A, Butler A et al (2019). Multidisciplinary management of spinal metastasis and vertebral instability: a systematic review. World neurosurgery, Vol 128, e944-e955.

    5. Levy J, Hopkins T, Morris J et al. (2020) Radiofrequency Ablation for the Palliative Treatment of Bone Metastases: Outcomes from the Multicenter OsteoCool Tumor Ablation Post-Market Study (OPuS One Study) in 100 Patients. J Vasc Interv Radiol; 31:1745–1752.

    6. Tomasian A, Marlow J, Hillen TJ et al. (2021) Complications of Percutaneous Radiofrequency Ablation of Spinal Osseous Metastases: An 8-Year Single-Center Experience. AJR. American journal of roentgenology; 1-7

    7. Lv N, Geng R, Ling F et al. (2020) Clinical efficacy and safety of bone cement combined with radiofrequency ablation in the treatment of spinal metastases. BMC Neurology, 20 : 418, pg 1-7 https://doi.org/10.1186/s12883-020-01998-5

    8. Jain S, Kinch L, Rana M et al (2020). Comparison of post-operative pain scores and opioid use between kyphoplasty and radiofrequency ablation (RFA) systems combined with cement augmentation. Skeletal Radiology (2020) 49:1789–1794

    9. Prezzano KM, Prasad D, Hermann GM et al (2019). Radiofrequency ablation and radiation therapy improve local control in spinal metastases compared to radiofrequency ablation alone. American Journal of Hospice & Palliative Medicine, Vol. 36(5) 417-422

    10. Lu WC, Shao J, Wu YG et al (2019). Which combination treatment Is better for spinal metastasis: percutaneous vertebroplasty with radiofrequency ablation, 125I Seed, Zoledronic Acid, or Radiotherapy? American journal of therapeutics. 26 (1), E38-E44.

    11. Huntoon K, Mostafa E, Moheyldin A et al (2020). Lower extremity paralysis after radiofrequency ablation of vertebral metastases. World neurosurgery. 133: 178-184.

    12. Coleman R, Hadji P, Body JJ et al. (2020) Bone health in cancer: ESMO Clinical Practice Guidelines. Annals of Oncology. 31 (12), 1650-1663.

    13. Swarm RA, Paice JA, Anghelescu DL et al. (2019). NCCN Clinical Practice Guidelines in Oncology. Adult Cancer Pain Version 3.2019 J Natl Compr Canc Netw 2019;17(8):977–1007.

    14. Tsoumakidou G, Too CW, Koch G et al (2017). CIRSE guidelines on percutaneous vertebral augmentation. Cardiovasc Intervent Radiol; 40:331-342.