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    The content on this page is not current guidance and is only for the purposes of the consultation process.

    Validity and generalisability of the studies

    • There are no prospective studies comparing percutaneous TDE with other treatments for managing chyle leaks. Studies were mainly retrospective analyses, heterogenous in terms of patient cohorts (with no clear definitions of chyle leak), aetiologies, and outcomes.

    • In 1 study retrograde thoracic duct access was used as a bail out approach in very few cases.

    • Quality of life was not assessed in any of the studies.