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1 Recommendations

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2 Information about nivolumab

Marketing authorisation indication

2.1 Nivolumab (Opdivo, Bristol Myers Squibb) 'in combination with fluoropyrimidine- and platinum-based combination chemotherapy is indicated for the first-line treatment of adult patients with unresectable advanced, recurrent or metastatic oesophageal squamous cell carcinoma with tumour cell PD-L1 expression ≥ 1%'.

Dosage in the marketing authorisation

2.2 The dosage schedule is available in the summary of product characteristics for nivolumab.

Price

2.3 The list price is £1,097 for a 100-mg vial (excluding VAT; BNF online accessed September 2022). The company has a commercial arrangement. This makes nivolumab available to the NHS with a discount. The size of the discount is commercial in confidence. It is the company's responsibility to let relevant NHS organisations know details of the discount.