How are you taking part in this consultation?

You will not be able to change how you comment later.

You must be signed in to answer questions

    The content on this page is not current guidance and is only for the purposes of the consultation process.

    Methods

    NICE identified studies and reviews relevant to endoscopic sleeve gastroplasty for obesity from the medical literature. The following databases were searched between the date they started to 22.02.2023: MEDLINE, PREMEDLINE, EMBASE, Cochrane Library and other databases. Trial registries and the internet were also searched (see the table 4 literature search strategy). Relevant published studies identified during consultation or resolution that are published after this date may also be considered for inclusion.

    The following inclusion criteria were applied to the abstracts identified by the literature search:

    • Publication type: clinical studies were included with emphasis on identifying good quality studies. Abstracts were excluded if they did not report clinical outcomes. Reviews, editorials, and laboratory or animal studies, were also excluded and so were conference abstracts, because of the difficulty of appraising study methodology, unless they reported specific adverse events that were not available in the published literature.

    • Patients with obesity.

    • Intervention or test: endoscopic sleeve gastroplasty.

    • Outcome: articles were retrieved if the abstract contained information relevant to the safety, efficacy, or both.

    If selection criteria could not be determined from the abstracts the full paper was retrieved.

    Potentially relevant studies not included in the main evidence summary are listed in the section on other relevant studies.

    Find out more about how NICE selects the evidence for the committee.

    Table 4 literature search strategy

    Databases

    Date searched

    Version/files

    MEDLINE (Ovid)

    22/02/2023

    1946 to February 21, 2023

    MEDLINE In-Process (Ovid)

    22/02/2023

    1946 to February 21, 2023

    MEDLINE Epubs ahead of print (Ovid)

    22/02/2023

    February 21, 2023

    EMBASE (Ovid)

    22/02/2023

    1974 to February 21, 2023

    Cochrane Database of Systematic Reviews – CDSR (Cochrane Library)

    22/02/2023

    Issue 2 of 12, February 2023

    Cochrane Central Database of Controlled Trials – CENTRAL (Cochrane Library)

    22/02/2023

    Issue 2 of 12, February 2023

    International HTA database (INAHTA)

    22/02/2023

    -

    Trial sources searched

    • Clinicaltrials.gov

    • ISRCTN

    • WHO International Clinical Trials Registry

    Websites searched

    • National Institute for Health and Care Excellence (NICE)

    • NHS England

    • Food and Drug Administration (FDA) - MAUDE database

    • Australian Safety and Efficacy Register of New Interventional Procedures – Surgical (ASERNIP – S)

    • Australia and New Zealand Horizon Scanning Network (ANZHSN)

    • General internet search

    The following search strategy was used to identify papers in MEDLINE. A similar strategy was used to identify papers in other databases.

    MEDLINE search strategy

    The MEDLINE search strategy was translated for use in the other sources.

    1        Gastroplasty/        4564

    2        Gastroplast*.tw.        1962

    3        or/1-2        5313

    4        Endoscopy/        58464

    5        endoscop*.tw.        204478

    6        4 or 5        221821

    7        3 and 6        683

    8        ((Endoscopic adj4 sleeve adj4 (gastroplast* or (gastr* adj4 surger*))) or ESG).tw.        487

    9        (Endoscopic adj4 (gastroplast* or (gastr* adj4 surger*))).tw.        433

    10        (endoscopic adj4 sutur*).tw.        703

    11        ((endosleeve or endolum?nal) adj4 (procedure* or surger*)).tw.        371

    12        POSE-2.tw.        12

    13        or/7-12        2253

    14        Obesity, Morbid/        25562

    15        ((Obese or Obesity or obesities) adj4 (Morbid* or sever*)).tw.        26378

    16        Body Mass Index/        147081

    17        ("body mass index" or BMI).tw.        266185

    18        Weight Loss/        42821

    19        (weight adj4 (loss* or reduc*)).tw.        127413

    20        or/14-19        436184

    21        13 and 20        564

    22        Overstitch.tw.        59

    23        Endomina.tw.        1

    24        or/21-23        606

    25        Animals/ not Humans/        5060243

    26        24 not 25        595