Interventional procedure overview of epidermal radiotherapy using rhenium-188 paste for non-melanoma skin cancer
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Methods
NICE identified studies and reviews relevant to epidermal radiotherapy using rhenium-188 paste from the medical literature. The following databases were searched between the date they started to 28th April 2023: MEDLINE, PREMEDLINE, EMBASE, Cochrane Library and other databases. Trial registries and the internet were also searched (see the literature search strategy). Relevant published studies identified during consultation or resolution that are published after this date may also be considered for inclusion.
The following inclusion criteria were applied to the abstracts identified by the literature search.
Publication type: clinical studies were included with emphasis on identifying good quality studies. Abstracts were excluded if they did not report clinical outcomes. Reviews, editorials, and laboratory or animal studies, were also excluded and so were conference abstracts, because of the difficulty of appraising study methodology, unless they reported specific adverse events that not available in the published literature.
Patients with non-melanoma skin cancer.
Intervention or test: Rhenium-188 paste.
Outcome: articles were retrieved if the abstract contained information relevant to the safety, efficacy, or both.
If selection criteria could not be determined from the abstracts the full paper was retrieved.
Potentially relevant studies not included in the main evidence summary are listed in the section on other relevant studies.
Find out more about how NICE selects the evidence for the committee.
Databases | Date searched | Version/files |
|---|---|---|
MEDLINE (Ovid) | 28/04/2023 | 1946 to April 27, 2023 |
MEDLINE In-Process (Ovid) | 28/04/2023 | 1946 to April 27, 2023 |
MEDLINE Epubs ahead of print (Ovid) | 28/04/2023 | April 27, 2023 |
EMBASE (Ovid) | 28/04/2023 | 1974 to April 27, 2023 |
EMBASE Conference (Ovid) | 28/04/2023 | 1974 to April 27, 2023 |
Cochrane Database of Systematic Reviews – CDSR (Cochrane Library) | 28/04/2023 | Issue 4 of 12, April 2023 |
Cochrane Central Database of Controlled Trials – CENTRAL (Cochrane Library) | 28/04/2023 | Issue 4 of 12, April 2023 |
International HTA database (INAHTA) | 28/04/2023 | - |
Trial sources searched
Clinicaltrials.gov
ISRCTN
WHO International Clinical Trials Registry
Websites searched
National Institute for Health and Care Excellence (NICE)
NHS England
Food and Drug Administration (FDA) - MAUDE database
Australian Safety and Efficacy Register of New Interventional Procedures – Surgical (ASERNIP – S)
Australia and New Zealand Horizon Scanning Network (ANZHSN)
General internet search
The following search strategy was used to identify papers in MEDLINE. A similar strategy was used to identify papers in other databases.
1 (("non melanoma*" or non-melanoma* or nonmelanoma*) adj4 skin adj4 (cancer* or tumo?r* or neoplasm* or carcinoma*)).tw. 5401
2 NMSC.tw. 1407
3 Carcinoma, Basal Cell/ 18639
4 (Basal Cell adj4 (Carcinoma* or Epithelioma*)).tw. 14713
5 (Rodent adj4 Ulcer*).tw. 99
6 Carcinoma, Squamous Cell/ 140111
7 ((Squamous or Epidermoid or Planocellular) adj4 carcinoma*).tw. 112747
8 (BCC or SCC).tw. 25717
9 (keratinocyte adj4 (cancer* or tumo?r* or neoplasm* or carcinoma*)).tw. 868
10 or/1-9 198634
11 Rhenium/ 2170
12 ((Rhenium adj2 "188") or "Rhenium-188").tw. 283
13 Brachytherapy/ 21695
14 (brachytherap* or curietherap*).tw. 17481
15 13 or 14 25127
16 ((High adj4 dose) or HDR or (Dermo adj4 beta)).tw. 118264
17 15 and 16 5090
18 (((beta adj4 emitter) or epiderm*) adj4 radioisotope*).tw. 4
19 (radioactive adj4 resin*).tw. 40
20 11 or 12 or 17 or 18 or 19 7359
21 10 and 20 620
22 (Oncobeta or Rhenium-SCT).tw. 2
23 21 or 22 620
24 Animals/ not Humans/ 5081619
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