Interventional procedure overview of temperature control to improve neurological outcomes after cardiac arrest
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Outcome measures
The main outcomes included survival and neurological outcomes. The measures used are detailed in the following paragraphs.
A range of validated instruments are used to evaluate neurological outcome including:
Cerebral performance categories (CPC): this is a 5-category measure used to assess neurological outcome. Categories 1 (good cerebral performance: conscious, alert, capable of normal life) and 2 (moderate cerebral disability: conscious, alert, sufficient cerebral function for activities of daily life) are considered to indicate a good neurological outcome. Categories 3 (severe cerebral disability), 4 (coma/vegetative state) and 5 (certified brain death) are considered to be a poor neurological outcome.
Pittsburgh cerebral performance category: this is a 4-level illness severity score of 1 (good recovery), 2 (moderate disability), 3 (severe disability) or 4 (coma).
The modified Rankin Scale: this is used to measure the degree of disability of people who have suffered a stroke or other causes or neurologic disability. The scale ranges from 0 to 6, with 0 for no symptoms, 3 for moderate disability (requires some help but able to walk without assistance), and 6 for dead.
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