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2 Information about ruxolitinib

Marketing authorisation indication

2.1 Ruxolitinib (Jakavi, Novartis Pharmaceuticals) is indicated for 'the treatment of adult patients with polycythaemia vera who are resistant to or intolerant of hydroxyurea [hydroxycarbamide]'.

Dosage in the marketing authorisation

2.2 The dosage schedule is available in the summary of product characteristics for ruxolitinib.

Price

2.3 The list prices of ruxolitinib for 56‑capsule packs are £1,428 (5 mg), £2,856 (10 mg), £2,856 (15 mg) and £2,856 (20 mg; all prices excluding VAT; BNF online accessed May 2023).

2.4 The company has a commercial arrangement. This makes ruxolitinib available to the NHS with a discount and it would have also applied to this indication if the technology had been recommended. The size of the discount is commercial in confidence. It is the company's responsibility to let relevant NHS organisations know details of the discount.