Interventional procedure overview of image-guided transperineal laser ablation (TPLA) for treating lower urinary tract symptoms caused by benign prostatic hyperplasia
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Unmet need
Lower urinary tract symptoms caused by BPH are a major burden for the ageing population, occurring in up to 30% of people aged over 65 with a prostate. There are a number of established and effective medical and surgical treatments for BPH. Potential complications of some of the surgical procedures include bleeding, infection, urethral strictures, incontinence and sexual dysfunction. There is a need for surgical treatments that are as effective as established treatment but have a reduced frequency of these complications. This procedure is potentially suitable for all prostate sizes and would be done as a day-case procedure under local or regional anaesthesia. Professional experts noted that this procedure may be of particular benefit for people:
whose BPH is unresponsive to medical therapy
on anticoagulants
with significant comorbidities
for whom alpha-blockers are contraindicated
for whom surgical treatment under general or spinal anaesthesia is not suitable
older people with long-term catheters
young people who want to minimise the risk of sexual dysfunction and incontinence
with large median lobes or prostate volume lower than 100 cc.
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