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Draft guidance

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2 Information about burosumab

Marketing authorisation indication

2.1

Burosumab (Crysvita, Kyowa Kirin) is indicated for 'the treatment of X-linked hypophosphataemia in children and adolescents aged 1 to 17 years with radiographic evidence of bone disease, and in adults'.

Price

2.3

The list prices per vial of solution for injection are £2,992 for 10 mg/1 ml, £5,984 for 20 mg/1 ml, and £8,976 for 30 mg/1 ml (excluding VAT; BNF online accessed November 2023).

2.4

The company has a commercial arrangement. This makes burosumab available to the NHS with a discount and it would have also applied to this indication if the technology had been recommended. The size of the discount is commercial in confidence. It is the company's responsibility to let relevant NHS organisations know details of the discount.