Evidence generation plan
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5 Minimum evidence standards
Neupulse has some clinical evidence suggesting that it may improve symptoms of tic disorders and Tourette syndrome in young people and adults. The technology did not report any safety concerns when using the digital technology to support treatment of tic disorders and Tourette syndrome.
In addition to the evidence above, the committee has indicated that it may in the future be able to recommend technologies in this topic area that have evidence for:
a beneficial impact of the digital technologies compared with standard care for treating tic disorders and Tourette syndrome without digital technologies
a clinical improvement in tic disorders and Tourette syndrome using the Yale Global Tic Severity Rating Scale total scoring
resource use associated with the technologies and NHS standard care
intervention acceptance, completion rates, patient preference, and uptake rates
the safe use of the technology (including all adverse events).
The company can strengthen the evidence base by also having evidence for:
effects on health-related quality of life measured through the EQ-5D
effectiveness in different subgroups
where the technology is used in the care pathway.
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