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    Are the summaries of clinical and cost effectiveness reasonable interpretations of the evidence?

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3 Information about zilucoplan

Marketing authorisation indication

3.1

Zilucoplan (Zilbrysq, UCB Pharma) is indicated 'as an add-on to standard therapy for the treatment of generalised myasthenia gravis (gMG) in adult patients who are anti-acetylcholine receptor (AChR) antibody positive'.

Dosage in the marketing authorisation

Price

3.3

The list price of zilucoplan is £3,653.97 for 7 pre-filled syringes of 16.6 mg solution for injection, £5,041.78 for 7 pre-filled syringes of 23.0 mg solution for injection, and £7,114.70 for 7 pre-filled syringes of 32.4 mg solution for injection (all excluding VAT, BNF online, accessed June 2024).

3.4

The company has a commercial arrangement, which would have applied if zilucoplan had been recommended.