Guidance
Update information
October 2017: We have updated the information on the off-label use of entecavir in the sections on children, young people and adults with compensated liver disease and decompensated liver disease who are taking entecavir or lamivudine.
January 2014: A correction has been made to the units used for ALT in men and women. The abnormal ALT levels should read greater than or equal to 30 IU/L for males and greater than or equal to 19 IU/L for females, not IU/ml. This has been changed in the relevant recommendations and recommendation for research 2.
June 2013: Recommendations in this guideline update and replace recommendations 1.2 to 1.4 in adefovir dipivoxil and peginterferon alfa-2a for the treatment of chronic hepatitis B (NICE technology appraisal guidance 96). NICE technology appraisal guidance 153, 154, 173 and recommendation 1.1 of NICE technology appraisal guidance 96 have been incorporated into this guideline.
Minor changes since publication
September 2024: We added links to relevant technology appraisal guidance in the section on antiviral treatment.
ISBN: 978-1-4731-4724-9