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PredictSURE IBD and IBDX to guide treatment of Crohn’s disease

Diagnostics guidance [DG45] Published: 23 February 2022

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Research recommendation(s) from an individual piece of guidance

Guidance:
PredictSURE IBD and IBDX to guide treatment of Crohn’s disease
Date issued:
23 February 2022

Research recommendations coming out of this guidance

  • The committee recommends more research on:

    • the accuracy of PredictSURE IBD and IBDX tests in identifying people at high or low risk of following a severe course of Crohn's disease
    • how PredictSURE IBD and IBDX tests, when used alongside clinical features, affect clinical decisions about whether step-up or top-down treatment is offered
    • the clinical outcomes and costs resulting from a top-down treatment strategy compared with a step-up treatment strategy
    • how PredictSURE IBD and IBDX tests affect clinical outcomes once someone has been assigned to top-down or step-up treatment, considering the different pathways that children and adults may follow.