Suggested remit: To appraise the clinical and cost effectiveness of tislelizumab within its marketing authorisation for treating unresectable advanced oesophageal squamous cell cancer after platinum-based chemotherapy.
 
Status In progress
Technology type Medicine
Decision Selected
Reason for decision Anticipate the topic will be of importance to patients, carers, professionals, commissioners and the health of the public to ensure clinical benefit is realised, inequalities in use addressed, and help them make the best use of NHS resources
Process Cost Comparison Standard
ID number 4070

Project Team

Project lead Jeremy Powell

Email enquiries

External Assessment Group Health Economics Research Unit and Health Services Research Unit, University of Aberdeen

Stakeholders

Companies sponsors BeiGene (tislelizumab)
Others Department of Health and Social Care
  NHS England
Patient carer groups Black Health Agency for Equality
  Cancer 52
  Cancer Black Care
  Cancer Equality
  GIST Cancer UK
  GUTS UK
  Heartburn Cancer UK
  Helen Rollason Cancer Charity
  Independent Cancer Patients Voice
  Macmillan Cancer Support
  Maggie’s Centres
  Marie Curie
  Ochre
  Oesophageal Patients Association
  OG Support formerly Together Support Group
  South Asian Health Foundation
  Specialised Healthcare Alliance
  Tenovus Cancer Care
Professional groups Association of Anaesthetists
  Association of Cancer Physicians
  Association of Surgeons of Great Britain and Ireland
  Association of Upper Gastrointestinal Surgeons of Great Britain and Ireland
  British Association of Surgical Oncology
  British Geriatrics Society
  British Institute of Radiology
  British Oncology Pharmacy Association
  British Psychosocial Oncology Society
  British Society of Gastroenterology
  Cancer Research UK
  Primary Care Society for Gastroenterology
  Royal College of Anaesthetists
  Royal College of General Practitioners
  Royal College of Nursing
  Royal College of Pathologists
  Royal College of Physicians
  Royal College of Radiologists
  Royal College of Surgeons
  Royal Pharmaceutical Society
  Royal Society of Medicine
  Society and College of Radiographers
  UK Clinical Pharmacy Association
  UK Oncology Nursing Society
Associated public health groups Public Health Wales
  UK Health Security Agency
Comparator companies Bristol Myers Squibb Pharmaceuticals (nivolumab)
General commentators All Wales Therapeutics and Toxicology Centre
  Allied Health Professionals Federation
  Board of Community Health Councils in Wales
  British National Formulary
  Care Quality Commission
  Department of Health - Northern Ireland
  Healthcare Improvement Scotland
  Medicines and Healthcare products Regulatory Agency
  National Association of Primary Care
  National Pharmacy Association
  NHS Confederation
  Scottish Medicines Consortium
  Welsh Government
  Welsh Health Specialised Services Committee
Relevant research groups Genomics England
  Institute of Cancer Research
  MRC Clinical Trials Unit
  National Institute for Health Research

Timeline

Key events during the development of the guidance:

Date Update
25 November 2024 Invitation to participate
15 July 2024 - 12 August 2024 Consultation on suggested remit, draft scope and provisional stakeholder list of consultees and commentators: 4070
15 July 2024 In progress. Scoping commencing
15 July 2024 In progress. Scoping commencing
02 July 2024 Please note that following an update from the company the timelines for this appraisal are anticipated to begin in mid-October 2024 when we will write to you about how you can get involved.
02 July 2024 Please note that following an update from the company the timelines for this appraisal are anticipated to begin in mid-October 2024 when we will write to you about how you can get involved.
16 January 2024 For information, tislelizumab has now been acquired by the company Beigene. NICE are liaising with the company regarding appropriate timelines for this appraisal and further information will be available in due course.
01 August 2023 Suspended. The company has informed NICE that it will not provide an evidence submission for this appraisal. Therefore, we are suspending the appraisal while we consider the next steps.
09 November 2022 Awaiting development. Status change linked to Topic Selection Decision being set to Selected
26 August 2022 Please note that following on from advice received from the company the timelines for this appraisal have been revised. We now anticipate that the appraisal will begin during early March 2023.

For further information on our processes and methods, please see our CHTE processes and methods manual