Status In progress
Technology type Medicine
Decision Selected
Reason for decision Anticipate the topic will be of importance to patients, carers, professionals, commissioners and the health of the public to ensure clinical benefit is realised, inequalities in use addressed, and help them make the best use of NHS resources
Process STA Standard
ID number 6342

Provisional Schedule

Committee meeting 05 December 2024
Expected publication 26 February 2025

Project Team

Project lead Leena Issa

Email enquiries

External Assessment Group Warwick Evidence, Warwick Medical School, University of Warwick

Stakeholders

Companies sponsors Pfizer (marstacimab)
Others Department of Health and Social Care
  NHS England
Patient carer groups Gene People
  The Haemophilia Society
Professional groups Royal College of Physicians
Associated public health groups None
Comparator companies Bio Products Laboratory (factor IX, factor VIII) (confidentiality agreement not signed, not participating)
  CSL Behring (etranacogene dezaparvovec, factor IX, factor VIII) (confidentiality agreement signed, participating)
  Grifols UK (factor IX, factor VIII) (confidentiality agreement not signed, not participating)
  Novo Nordisk Ltd (factor VIII, eptacog alfa, nonacog beta pegol, turoctocog alfa pegol) (confidentiality agreement signed, participating)
  Octapharma (factor VIII, simoctocog alfa) (confidentiality agreement not signed, not participating)
  Pfizer (fidanacogene elaparvovec, moroctocog alfa, nonacog alfa) (confidentiality agreement not signed, not participating)
  Roche products (emicizumab) (confidentiality agreement signed, participating)
  Swedish Orphan Biovitrum (efanesoctocog alfa, efmoroctocog alfa, eftrenonacog alfa) (confidentiality agreement signed, participating)
  Takeda (factor IX, factor VIII, octocog alfa, rurioctocog alfa pegol, susoctocog alfa) (confidentiality agreement not signed, not participating)
General commentators All Wales Therapeutics and Toxicology Centre
  British National Formulary
  Department of Health – Northern Ireland
  Haemophilia Northern Ireland
  Healthcare Improvement Scotland
  Medicines and Healthcare products Regulatory Agency
  Scottish Medicines Consortium
  Welsh Government
  Welsh Health Specialised Services Committee
Relevant research groups None

Timeline

Key events during the development of the guidance:

Date Update
16 May 2024 Invitation to participate
07 March 2024 - 08 April 2024 Consultation on suggested remit, draft scope and provisional stakeholder list of consultees and commentators: 6342
07 March 2024 In progress. Scoping commenced.
26 February 2024 Expected publication
30 August 2023 Awaiting development. Status change linked to Topic Selection Decision being set to Selected

For further information on our processes and methods, please see our CHTE processes and methods manual