Suggested remit: To appraise the clinical and cost effectiveness of delgocitinib within its marketing authorisation for treating moderate to severe chronic hand eczema.
 
Status In progress
Technology type Medicine
Decision Selected
Reason for decision Anticipate the topic will be of importance to patients, carers, professionals, commissioners and the health of the public to ensure clinical benefit is realised, inequalities in use addressed, and help them make the best use of NHS resources
Process STA Standard
ID number 6408

Provisional Schedule

Committee meeting: 1 04 June 2025
Expected publication 13 August 2025

Project Team

Project lead Vonda Murray

Email enquiries

External Assessment Group BMJ Technology Assessment Group (BMJ-TAG), BMJ

Stakeholders

Companies sponsors Leo Pharma
Others Department of Health and Social Care
  Health Technology Wales (HTW)
  NHS England
Patient carer groups National Eczema Society
Professional groups British Association of Dermatologists
  Royal College of Physicians
Comparator companies AAH Pharmaceuticals (alitretinoin, tacrolimus) (confidentiality agreement not signed, not participating), Accord UK (tacrolimus) (confidentiality agreement not signed, not participating), Advanz Pharma (methotrexate) (confidentiality agreement not signed, not participating), Aspen (azathioprine, mycophenolate mofetil) (confidentiality agreement not signed, not participating), Cipla UK (methotrexate) (confidentiality agreement not signed, not participating)
  Dexcel Pharma (ciclosporin) (confidentiality agreement not signed, not participating), Ennogen Healthcare (alitretinoin) (confidentiality agreement not signed, not participating), Hospira (methotrexate) (confidentiality agreement not signed, not participating), Leo Pharma (tacrolimus) (confidentiality agreement not signed, not participating), Medac (methotrexate) (confidentiality agreement not signed, not participating), Medihealth (tacrolimus) (confidentiality agreement not signed, not participating), Morningside Healthcare (methotrexate) (confidentiality agreement not signed, not participating), Mylan (azathioprine; ciclosporin, (confidentiality agreement not signed, not participating)mycophenolate mofetil), Nordic Pharma (methotrexate) (confidentiality agreement not signed, not participating)
  Nova (azathioprine; mycophenolate mofetil) (confidentiality agreement not signed, not participating), Novartis (ciclosporin) (confidentiality agreement not signed, not participating), Orion Pharma (methotrexate) (confidentiality agreement not signed, not participating), Rosemont Pharmaceuticals (methotrexate) (confidentiality agreement not signed, not participating)
  Sandoz (methotrexate,) (confidentiality agreement not signed, not participating), Santen UK (ciclosporin) (confidentiality agreement not signed, not participating), Strides Pharma (azathioprine, mycophenolate mofetil) (confidentiality agreement not signed, not participating)
  Teva UK (tacrolimus) (confidentiality agreement not signed, not participating)
  Tillomed Laboratories (azathioprine, mycophenolate mofetil) (confidentiality agreement not signed, not participating), Viatris (pimecrolimus) (confidentiality agreement not signed, not participating)
  Stiefel Laboratories (alitretinoin) (confidentiality agreement signed, participating)
General commentators All Wales Therapeutics and Toxicology Centre
  British National Formulary
  Department of Health - Northern Ireland
  Healthcare Improvement Scotland
  Medicines and Healthcare products Regulatory Agency
  Scottish Medicines Consortium
  Welsh Government
  Welsh Health Specialised Services Committee

Timeline

Key events during the development of the guidance:

Date Update
22 October 2024 Invitation to participate
17 July 2024 - 14 August 2024 Consultation on suggested remit, draft scope and provisional stakeholder list of consultees and commentators
17 July 2024 In progress. Scoping commencing
31 January 2024 Awaiting development. Status change linked to Topic Selection Decision being set to Selected
30 January 2024 Topic selection

For further information on our processes and methods, please see our CHTE processes and methods manual