NICE did a rapid review of the published literature on the efficacy and safety of this procedure. This comprised a comprehensive literature search and detailed review of the evidence from 3 sources, which was discussed by the committee. The evidence included 3 case series. It is presented in the summary of key evidence section in the interventional procedures overview. Other relevant literature is in the appendix of the overview.
The professional experts and the committee considered the key efficacy outcomes to be pain reduction, reduction in analgesia, and improved quality of life.
The professional experts and the committee considered the key safety outcomes to be pain, bleeding, infection, and inadvertent kidney damage.
Patient commentary was sought but none was received.
There are other methods of denervating the kidney, some of which are less invasive.
The pathophysiology of loin pain haematuria syndrome and the method of action of renal denervation for the treatment of this condition are unclear.
ISBN: 978-1-4731-4305-0