Recommendations for research
The guideline committee has made the following recommendations for research.
1 Initial investigations for people with suspected adrenal insufficiency
What is the clinical and cost effectiveness of salivary cortisone or cortisol to identify people with adrenal insufficiency?
For a short explanation of why the committee made this recommendation for research, see the rationale section on initial investigations .
Full details of the evidence and the committee's discussion are in evidence review D: diagnostic tests and thresholds for referral.
2 Glucocorticoid withdrawal
In people at risk of adrenal insufficiency because of prolonged glucocorticoid use, what is the best way to manage glucocorticoid withdrawal when they are no longer needed?
For a short explanation of why the committee made this recommendation for research, see the rationale section on managing glucocorticoid withdrawal to prevent adrenal insufficiency .
Full details of the evidence and the committee's discussion are in evidence review E: methods for corticosteroid withdrawal.
3 Adrenal crisis
What increases the risk of adrenal crisis and adverse hospital outcomes in people taking long-term corticosteroids?
For a short explanation of why the committee made this recommendation for research, see the rationale section on when to suspect adrenal crisis .
Full details of the evidence and the committee's discussion are in evidence review H: when to suspect adrenal crisis.
4 Routine pharmacological management in secondary and tertiary adrenal insufficiency
What is the clinical and cost effectiveness of glucocorticoids for the routine management of secondary and tertiary adrenal insufficiency?
For a short explanation of why the committee made this recommendation for research, see the rationale section on routine pharmacological management .
Full details of the evidence and the committee's discussion are in evidence review G: routine pharmacological management of secondary and tertiary adrenal insufficiency.
5 Pharmacological management of physiological stress
What is the clinical and cost effectiveness of postoperative glucocorticoids for people with, or at risk of, adrenal insufficiency having inpatient invasive procedures?
For a short explanation of why the committee made this recommendation for research, see the rationale section on management during physiological stress .
Full details of the evidence and the committee's discussion are in evidence review J: pharmacological management of physiological stress.