Guidance
Recommendations for research
Recommendations for research
The guideline committee has made the following recommendations for research.
1 Initial investigations for people with suspected adrenal insufficiency
What is the clinical and cost effectiveness of salivary cortisone or cortisol to identify people with adrenal insufficiency?
For a short explanation of why the committee made this recommendation for research, see the rationale section on initial investigations.
Full details of the evidence and the committee's discussion are in evidence review D: diagnostic tests and thresholds for referral.
2 Glucocorticoid withdrawal
In people at risk of adrenal insufficiency because of prolonged glucocorticoid use, what is the best way to manage glucocorticoid withdrawal when they are no longer needed?
For a short explanation of why the committee made this recommendation for research, see the rationale section on managing glucocorticoid withdrawal to prevent adrenal insufficiency.
Full details of the evidence and the committee's discussion are in evidence review E: methods for corticosteroid withdrawal.
3 Adrenal crisis
What increases the risk of adrenal crisis and adverse hospital outcomes in people taking long-term corticosteroids?
For a short explanation of why the committee made this recommendation for research, see the rationale section on when to suspect adrenal crisis.
Full details of the evidence and the committee's discussion are in evidence review H: when to suspect adrenal crisis.
4 Routine pharmacological management in secondary and tertiary adrenal insufficiency
What is the clinical and cost effectiveness of glucocorticoids for the routine management of secondary and tertiary adrenal insufficiency?
For a short explanation of why the committee made this recommendation for research, see the rationale section on routine pharmacological management.
Full details of the evidence and the committee's discussion are in evidence review G: routine pharmacological management of secondary and tertiary adrenal insufficiency.
5 Pharmacological management of physiological stress
What is the clinical and cost effectiveness of postoperative glucocorticoids for people with, or at risk of, adrenal insufficiency having inpatient invasive procedures?
For a short explanation of why the committee made this recommendation for research, see the rationale section on management during physiological stress.
Full details of the evidence and the committee's discussion are in evidence review J: pharmacological management of physiological stress.