2 Information about selpercatinib

Marketing authorisation indication

2.1

Selpercatinib (Retsevmo, Eli Lilly) as monotherapy is indicated for 'the treatment of adults with advanced RET fusion-positive non-small cell lung cancer (NSCLC) not previously treated with a RET inhibitor'.

Dosage in the marketing authorisation

Price

2.3

The list price for selpercatinib is £2,184 per pack of 56 x 40 mg capsules; £6,552 per pack of 168 x 40 mg capsules; £4,368 per pack of 56 x 80 mg capsules and £8,736 per pack of 112 x 80 mg capsules (excluding VAT; BNF online, accessed September 2024).

2.4

The company has a commercial arrangement. This makes selpercatinib available to the NHS with a discount. The size of the discount is commercial in confidence.