People with malignant glioma can suffer from a range of symptoms and impairments. Some symptoms may be general and others may be specific to the area of brain where the tumour is located. General symptoms include headache, anorexia, nausea, vomiting, seizures, drowsiness, personality changes, and cognitive slowing. More focal (specific) symptoms could include difficulties with hearing, speech, ambulation, dexterity, visual difficulties, and mood disturbances. These symptoms can have a profound effect on the quality of life of the patient as well as their ability to work and to care for themselves. A significant physical and emotional burden is often placed on carers, particularly as the disease progresses.