6 Sources of evidence considered by the Committee

The Evidence Review Group (ERG) report for this appraisal was prepared by Liverpool Reviews and Implementation Group (LRiG):

  • Fleeman N, Bagust A, Boland A et al. Fulvestrant for the treatment of locally advanced or metastatic breast cancer: a single technology appraisal (June 2011)

The following organisations accepted the invitation to participate in this appraisal as consultees and commentators. They were invited to comment on the draft scope, the ERG report and the appraisal consultation document (ACD). Manufacturers or sponsors were also invited to make written submissions. Professional or specialist, patient or carer groups, and other consultees, had the opportunity to give their expert views. Manufacturers or sponsors, professional or specialist, patient or carer groups, and other consultees, also have the opportunity to appeal against the final appraisal determination.

Manufacturers or sponsors:

  • AstraZeneca

Professional or specialist, and patient or carer groups:

  • Breakthrough Breast Cancer

  • Breast Cancer Campaign

  • Breast Cancer Care

  • Macmillan Cancer Support

  • Cancer Research UK

  • Royal College of Nursing

  • Royal College of Pathologists

  • Royal College of Physicians

Other consultees:

  • Department of Health

  • Welsh Government

Commentator organisations (did not provide written evidence and without the right of appeal):

  • Commissioning Support Appraisals Service

  • Department of Health, Social Services and Public Safety, Northern Ireland

  • Healthcare Improvement Scotland

  • AstraZeneca

  • Pfizer

  • Liverpool Reviews and Implementation Group

  • National Institute for Health Research Technology Assessment Programme

The following individuals were selected from clinical specialist and patient expert nominations from the non-manufacturer or sponsor consultees and commentators. They gave their expert personal view on fulvestrant by attending the initial Committee discussion and providing written evidence to the Committee. They are invited to comment on the ACD.

  • Dr Andreas Makris, Consultant Clinical Oncologist, nominated by Royal College of Physicians – clinical specialist

  • Tara Beaumont, Clinical Nurse Specialist, nominated by Breast Cancer Care – patient expert

  • Marie Hecht, nominated by Breast Cancer Care – patient expert

Representatives from the following manufacturer or sponsor attended Committee meetings. They contributed only when asked by the Committee chair to clarify specific issues and comment on factual accuracy.

  • AstraZeneca

ISBN: 978-1-4731-6693-6