3 Evidence

The appraisal committee (section 6) considered evidence submitted by Eli Lilly and Company and a review of this submission by the evidence review group (ERG). This appraisal was a Cancer Drugs Fund reconsideration of the published NICE technology appraisal guidance on pemetrexed for maintenance treatment following induction therapy with pemetrexed and cisplatin for non-squamous non-small-cell lung cancer. It focused on cost-effectiveness analyses using a commercial access agreement, which provides pemetrexed at a reduced cost for continuation maintenance treatment (that is, pemetrexed maintenance after pemetrexed and cisplatin induction therapy). The financial terms of the agreement are commercial in confidence. See the committee papers for full details of the Cancer Drugs Fund reconsideration evidence and the history for full details of the evidence used for NICE's original technology appraisal guidance on pemetrexed maintenance treatment after induction therapy with pemetrexed and cisplatin.